国际肿瘤学杂志

国际肿瘤学杂志››2012,Vol. 39››Issue (2): 133-136.

• 综述 •上一篇下一篇

遗传性乳腺癌易感基因

张新明, 高伟

  1. 266033 青岛市海慈医疗集团普外科
  • 出版日期:2012-02-08发布日期:2012-01-18
  • 通讯作者:高伟，E-mail: 1120866150@qq.com E-mail:1120866150@qq.com

Susceptibility genes of inherited breast cancer

ZHANG Xin-Ming, GAO Wei

  1. Department of General Surgery ,Qingdao Hiser Medical Center,Qingdao 266033,China
  • Online:2012-02-08Published:2012-01-18
  • Contact:Corresponding author: GAO Wei, E-mail: 1120866150@qq.com E-mail:1120866150@qq.com

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2254

被引次数

5

摘要：遗传性乳腺癌占所有乳腺癌患者的10%~25%。遗传因素对部分乳腺癌的发生发展具有重要作用。遗传性乳腺癌的易感基因包括高外显率易感基因、中外显率易感基因和低外显率易感基因。多种易感基因与遗传性乳腺癌密切相关。

Abstract:There are 10%~25% inherited breast cancer patients among all breast cancer patients. Hereditary factors play an important role in the occurrence and development of inherited breast cancer. There are three kinds of susceptibility genes of inherited breast cancer including high penetrance susceptibility genes, middle penetrance susceptibility genes and low penetrance susceptibility genes. Various susceptibility genes are closely related to inherited breast cancer.