国际肿瘤学杂志

国际肿瘤学杂志››2011,Vol. 38››Issue (12): 908-910.

• 综述 •上一篇下一篇

Th17细胞与肿瘤

何宋兵, 郑丁铖, 汪良, 等

  1. 215006苏州，苏州大学附属第一医院普外科
  • 出版日期:2011-12-08发布日期:2011-11-25
  • 通讯作者:汪良，E-mail：hesongbing2@yahoo.com.cn E-mail:hesongbing2@yahoo.com.cn
  • 基金资助:

    江苏省卫生厅医学科研计划资助项目H201013

T helper 17 cells and tumor

HE Song-Bing, ZHENG Ding-Cheng, WANG Liang, et al

  1. Department of General Surgery, First Affiliated Hospital of Soochow University, Suzhou 215006, China
  • Online:2011-12-08Published:2011-11-25
  • Contact:WANG Liang, E-mail: hesongbing2@yahoo.com.cn E-mail:hesongbing2@yahoo.com.cn

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摘要：Thl7细胞是一类CD4+效应T细胞。研究发现Thl7细胞及其相关细胞因子存在于许多肿瘤中，并在炎症相关性肿瘤中发挥重要作用，但对Thl7细胞在肿瘤微环境中的分化表达、免疫调控机制及功能效应仍不明确。

Abstract:Th17 cells are CD4+effector T cells. Many studies have confirmed that Th17 cells and their related cytokines exist in many kinds of tumors, and play critical roles in inflammation related tumors. But the expression and differentiation in tumor microenvironment, the immune regulation mechanisms and functional effects of Th17 cells remains controversial.