国际肿瘤学杂志››2012,Vol. 39››Issue (6): 432-435.

• 综述 •上一篇下一篇

乳腺癌分子分型及其临床意义

于双全,于志勇

  1. 济南,山东省肿瘤防治研究院乳腺病中心
  • 出版日期:2012-06-08发布日期:2012-06-25
  • 通讯作者:于志勇,E-mail:drzhiyongyu@yahoo.com.cn E-mail:drzhiyongyu@yahoo.com.cn
  • 基金资助:

    山东省科技发展计划项目(2011GSF11823)

Breast cancer molecular subtypes and its clinical significance

YU Shuang-quan, YU Zhi-yong

  1. Breast Cancer Center, Shandong Cancer Hospital, Jinan 250117, China
  • Online:2012-06-08Published:2012-06-25
  • Contact:YU Zhi-yong, E-mail: drzhiyongyu@yahoo.com.cn E-mail:drzhiyongyu@yahoo.com.cn

摘要:乳腺癌是具有高度异质性的肿瘤。组织学形态相同的肿瘤,其分子生物学改变不尽相同。不同的分子分型具有不同的生物学行为以及治疗的敏感性,基于基因表达谱和分子生物学特征为基础提出的乳腺癌分子生物学分型,能较好地反映肿瘤的生物学行为,具有重要的临床意义。

关键词:乳腺肿瘤,分子分型,肿瘤转移

Abstract:Breast cancer is regarded as a heterogenous disease classified into different molecular subtypes, resulting in different biologic behavior and sensitivity to treatment respectively. Molecular biology typing that based gene expression profiles and biological characteristics of breast cancer can reflect the biological behavior of tumors exactly, which has important clinical significance.

Key words:Breast neoplasms,Molecular typing,Neoplasm metastasis