小细胞肺癌脑转移的防治

国际肿瘤学杂志››2014,Vol. 41››Issue (8): 588-592.doi:10.3760/cma.j.issn.1673-422X.2014.08.010

高超,于甬华

250062 济南大学 betway.com 医学与生命科学学院（高超）；山东省肿瘤医院放疗二病区（高超、于甬华）

收稿日期:2014-02-24修回日期:2014-03-26出版日期:2014-08-15发布日期:2014-08-14
通讯作者:于甬华，E-mail：sdyonghuayu@163.com E-mail:sdyonghuayu@163.com

Prevention and therapy of small cell lung cancer with brain metastasis

Gao Chao, Yu Yonghua

School of Medicine and Life Sciences, University of Ji′nanShandong Academy of Medical Sciences; Second Department of Radiation Oncology, Shandong Cancer Hospital, Ji′nan 250062, China

Received:2014-02-24Revised:2014-03-26Online:2014-08-15Published:2014-08-14
Contact:Yu Yonghua E-mail:sdyonghuayu@163.com

摘要/Abstract

摘要：小细胞肺癌脑转移是脑转移性肿瘤中最常见的类型，且预后较差。研究表明，预防性全脑放疗不仅在局限期小细胞肺癌脑转移的预防和诊治中有效，对于广泛期同样有效。另外某些药物如甘露醇、尼莫司汀等同样起到了重要辅助作用，但是在预防和治疗方面还有很多不确定的地方，尚存争议，需要进一步研究。

关键词:癌,小细胞,肺肿瘤,肿瘤转移,放射疗法,药物疗法

Abstract:Small cell lung cancer with brain metastasis is the most common type in brain metastasis tumors with the poor prognosis. Researches show that prophylactic cranial irradiation is not only effective in the prevention and treatment of limited disease brain metastases of small cell lung cancer, but also effective for extensive disease. Moreover, certain medications such as mannitol, nimustine etc also play an important supporting role, but there are many other uncertain parts in terms of prevention and treatment remaining controversial and needing further research.

Key words:Carcinoma, small cell,Lung neoplasms,Neoplasm metastasis,Radiotherapy,Drug therapy

高超,于甬华. 小细胞肺癌脑转移的防治[J]. 国际肿瘤学杂志, 2014, 41(8): 588-592.

Gao Chao, Yu Yonghua. Prevention and therapy of small cell lung cancer with brain metastasis[J]. Journal of International Oncology, 2014, 41(8): 588-592.

参考文献

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