Research status of glioblastoma-associated microglia

Abstract

Fei Wenjing, Wang Wenbao, Xie Huanhuan, Yan Jing, Yang Mi. Research status of glioblastoma-associated microglia[J]. Journal of International Oncology, 2022, 49(7): 420-424.

References32

[1]	Wake H, Moorhouse AJ, Miyamoto A, et al. Microglia: actively surveying and shaping neuronal circuit structure and function[J]. Trends Neurosci, 2013, 36(4): 209-217. DOI: 10.1016/j.tins.2012.11.007. doi:10.1016/j.tins.2012.11.007
[2]	Stoessel MB, Majewska AK. Little cells of the little brain: microglia in cerebellar development and function[J]. Trends Neurosci, 2021, 44(7): 564-578. DOI: 10.1016/j.tins.2021.04.001. doi:10.1016/j.tins.2021.04.001pmid:33933255
[3]	Gosselin D, Skola D, Coufal NG, et al. An environment-dependent transcriptional network specifies human microglia identity[J]. Science, 2017, 356(6344): eaal3222. DOI: 10.1126/science.aal3222. doi:10.1126/science.aal3222
[4]	Brandenburg S, Blank A, Bungert AD, et al. Distinction of microglia and macrophages in glioblastoma: close relatives, different tasks?[J]. Int J Mol Sci, 2020, 22(1): 194. DOI: 10.3390/ijms22010194. doi:10.3390/ijms22010194
[5]	Haage V, Semtner M, Vidal RO, et al. Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma[J]. Acta Neuropathol Commun, 2019, 7(1): 20. DOI: 10.1186/s40478-019-0665-y. doi:10.1186/s40478-019-0665-y
[6]	Matias D, Dubois LG, Pontes B, et al. GBM-derived Wnt3a induces M2-like phenotype in microglial cells through Wnt/β-catenin signa-ling[J]. Mol Neurobiol, 2019, 56(2): 1517-1530. DOI: 10.1007/s12035-018-1150-5. doi:10.1007/s12035-018-1150-5pmid:29948952
[7]	Serpe C, Monaco L, Relucenti M, et al. Microglia-derived small extracellular vesicles reduce glioma growth by modifying tumor cell metabolism and enhancing glutamate clearance through miR-124[J]. Cells, 2021, 10(8): 2066. DOI: 10.3390/cells10082066. doi:10.3390/cells10082066
[8]	McGranahan T, Therkelsen KE, Ahmad S, et al. Current state of immunotherapy for treatment of glioblastoma[J]. Curr Treat Options Oncol, 2019, 20(3): 24. DOI: 10.1007/s11864-019-0619-4. doi:10.1007/s11864-019-0619-4
[9]	Henrik Heiland D, Ravi VM, Behringer SP, et al. Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma[J]. Nat Commun, 2019, 10(1): 2541. DOI: 10.1038/s41467-019-10493-6. doi:10.1038/s41467-019-10493-6pmid:31186414
[10]	Qian J, Luo F, Yang J, et al. TLR2 promotes glioma immune evasion by downregulating MHC class Ⅱ molecules in microglia[J]. Cancer Immunol Res, 2018, 6(10): 1220-1233. DOI: 10.1158/2326-6066.CIR-18-0020. doi:10.1158/2326-6066.CIR-18-0020
[11]	Chang CY, Jeon SB, Yoon HJ, et al. Glial TLR2-driven innate immune responses and CD8⁺T cell activation against brain tumor[J]. Glia, 2019, 67(6): 1179-1195. DOI: 10.1002/glia.23597. doi:10.1002/glia.23597
[12]	Dumas AA, Pomella N, Rosser G, et al. Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment[J]. EMBO J, 2020, 39(15): e103790. DOI: 10.15252/embj.2019103790. doi:10.15252/embj.2019103790
[13]	Lisi L, Ciotti GMP, Chiavari M, et al. Phospho-mTOR expression in human glioblastoma microglia-macrophage cells[J]. Neurochem Int, 2019, 129: 104485. DOI: 10.1016/j.neuint.2019.104485. doi:10.1016/j.neuint.2019.104485
[14]	Turkowski K, Brandenburg S, Mueller A, et al. VEGF as a modulator of the innate immune response in glioblastoma[J]. Glia, 2018, 66(1): 161-174. DOI: 10.1002/glia.23234. doi:10.1002/glia.23234pmid:28948650
[15]	Brandenburg S, Müller A, Turkowski K, et al. Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors[J]. Acta Neuropathol, 2016, 131(3): 365-378. DOI: 10.1007/s00401-015-1529-6. doi:10.1007/s00401-015-1529-6pmid:26718201
[16]	Haruwaka K, Ikegami A, Tachibana Y, et al. Dual microglia effects on blood brain barrier permeability induced by systemic inflammation[J]. Nat Commun, 2019, 10(1): 5816. DOI: 10.1038/s41467-019-13812-z. doi:10.1038/s41467-019-13812-z
[17]	Couto M, Coelho-Santos V, Santos L, et al. The interplay between glioblastoma and microglia cells leads to endothelial cell monolayer dysfunction via the interleukin-6-induced JAK2/STAT3 pathway[J]. J Cell Physiol, 2019, 234(11): 19750-19760. DOI: 10.1002/jcp.28575. doi:10.1002/jcp.28575
[18]	Litak J, Mazurek M, Grochowski C, et al. PD-L1/PD-1 axis in glioblastoma multiforme[J]. Int J Mol Sci, 2019, 20(21): 5347. DOI: 10.3390/ijms20215347. doi:10.3390/ijms20215347
[19]	Jenkinson MD, Santarius T, Zadeh G, et al. Atypical meningio-mais it time to standardize surgical sampling techniques?[J]. Neuro Oncol, 2017, 19(3): 453-454. DOI: 10.1093/neuonc/now245. doi:10.1093/neuonc/now245
[20]	Schalper KA, Rodriguez-Ruiz ME, Diez-Valle R, et al. Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma[J]. Nat Med, 2019, 25(3): 470-476. DOI: 10.1038/s41591-018-0339-5. doi:10.1038/s41591-018-0339-5pmid:30742120
[21]	Reardon DA, Brandes AA, Omuro A, et al. Effect of nivolumab vs bevacizumab in patients with recurrent glioblastoma: the CheckMate 143 phase 3 randomized clinical trial[J]. JAMA Oncol, 2020, 6(7): 1003-1010. DOI: 10.1001/jamaoncol.2020.1024. doi:10.1001/jamaoncol.2020.1024pmid:32437507
[22]	Liu X, Wu X, Wang Y, et al. CD47 promotes human glioblastoma invasion through activation of the PI3K/Akt pathway[J]. Oncol Res, 2019, 27(4): 415-422. DOI: 10.3727/096504018X15155538502359. doi:10.3727/096504018X15155538502359
[23]	Hu J, Xiao Q, Dong M, et al. Glioblastoma immunotherapy targe-ting the innate immune checkpoint CD47-SIRPα axis[J]. Front Immunol, 2020, 11: 593219. DOI: 10.3389/fimmu.2020.593219. doi:10.3389/fimmu.2020.593219
[24]	Hutter G, Theruvath J, Graef CM, et al. Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma[J]. Proc Natl Acad Sci U S A, 2019, 116(3): 997-1006. DOI: 10.1073/pnas.1721434116. doi:10.1073/pnas.1721434116
[25]	Prionisti I, Bühler LH, Walker PR, et al. Harnessing microglia and macrophages for the treatment of glioblastoma[J]. Front Pharmacol, 2019, 10: 506. DOI: 10.3389/fphar.2019.00506. doi:10.3389/fphar.2019.00506pmid:31231208
[26]	Menzel F, Kaiser N, Haehnel S, et al. Impact of X-irradiation on microglia[J]. Glia, 2018, 66(1): 15-33. DOI: 10.1002/glia.23239. doi:10.1002/glia.23239
[27]	Osman AM, Sun Y, Burns TC, et al. Radiation triggers a dynamic sequence of transient microglial alterations in juvenile brain[J]. Cell Rep, 2020, 31(9): 107699. DOI: 10.1016/j.celrep.2020.107699. doi:10.1016/j.celrep.2020.107699
[28]	Okonogi N, Suzuki Y, Sato H, et al. Combination therapy of intravenously injected microglia and radiation therapy prolongs survival in a rat model of spontaneous malignant glioma[J]. Int J Radiat Oncol Biol Phys, 2018, 102(3): 601-608. DOI: 10.1016/j.ijrobp.2018.06.018. doi:10.1016/j.ijrobp.2018.06.018
[29]	Wang Q, Hu B, Hu X, et al. Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment[J]. Cancer Cell, 2017, 32(1): 42-56.e6. DOI: 10.1016/j.ccell.2017.06.003. doi:10.1016/j.ccell.2017.06.003
[30]	Acharya MM, Green KN, Allen BD, et al. Elimination of microglia improves cognitive function following cranial irradiation[J]. Sci Rep, 2016, 6: 31545. DOI: 10.1038/srep31545. doi:10.1038/srep31545
[31]	Foray C, Valtorta S, Barca C, et al. Imaging temozolomide-induced changes in the myeloid glioma microenvironment[J]. Theranostics, 2021, 11(5): 2020-2033. DOI: 10.7150/thno.47269. doi:10.7150/thno.47269
[32]	Li J, Kaneda MM, Ma J, et al. PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response[J]. Proc Natl Acad Sci U S A, 2021, 118(16): e2009290118. DOI: 10.1073/pnas.2009290118. doi:10.1073/pnas.2009290118

Research status of glioblastoma-associated microglia

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