Journal of International Oncology››2014,Vol. 41››Issue (8): 570-573.doi:10.3760/cma.j.issn.1673-422X.2014.08.004

Previous ArticlesNext Articles

Application of microdialysis in tumor

Zhou Jingchao, Li Juan, Liu Chunsheng, Zhou Dinghua, Tong Weihang, Wang Dan

  1. Department of Pharmacy, Second Artillery General Hospital of PLA, Beijing 100088, China
  • Received:2014-03-06Revised:2014-04-18Online:2014-08-15Published:2014-08-14
  • Contact:Wang Dan E-mail:wdyy_618@sina.com

Abstract:Microdialysis is an automatic biological sampling technique that is directed into the target tissue. Microdialysis is used to monitor the changes of drug and related substances associated with pathological physiology of tumor in the target tissue at the molecular level. Microdialysis is applied to evaluate the pharmacokinetics of drugs in the target tissue of tumor, optimize the combination therapy, explore molecular targeted therapy and study the early diagnosis and prognosis of tumor. Microdialysis provides a new idea and method for the prevention and cure research of tumor.

Key words:Microdialysis,Neoplasms,Pharmacokinetics,Diagnosis,Prognosis,Molecular targeted therapy