Research progress of liquid biopsy in early diagnosis of lung cancer

Journal of International Oncology››2019,Vol. 46››Issue (9): 548-552.doi:10.3760/cma.j.issn.1673-422X.2019.09.008

Research progress of liquid biopsy in early diagnosis of lung cancer

Ding Yu¹, Qiao Guibin²#br#

¹Second Clinical Medical School, Southern Medical University, Guangzhou 510515, China;²Department of Thoracic Surgery, Guangdong Provincial People′s Hospital (Guangdong Academy of Medical Science), Guangzhou 510030, China

Received:2019-04-28Online:2019-09-08Published:2019-09-08
Contact:Qiao Guibin E-mail:guibinqiao@126.com

Abstract

Abstract:Liquid biopsy is a kind of emerging pathological detection technique, which has shown certain value in the diagnosis and treatment of lung cancer. Detections of circulating tumor cells, circulating tumor DNA, DNA methylation, microRNA, exosomes and tumor educated platelets in patients′ body fluids can be used for the early diagnosis and predicting the progress of lung cancer. At recent, the application of liquid biopsy still has some shortcomings. However, with the continuous development of detection technology, it may become an effective auxiliary or alternative method for imaging examination such as CT in the near future, and will provide a new direction for the diagnosis and treatment of lung cancer.

Key words:Lung neoplasms,Diagnosis,Liquid biopsy

Ding Yu, Qiao Guibin. Research progress of liquid biopsy in early diagnosis of lung cancer[J]. Journal of International Oncology, 2019, 46(9): 548-552.

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Research progress of liquid biopsy in early diagnosis of lung cancer

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