Abstract:T-cell non-Hodgkin lymphoma is a group disease with unique clinical and pathological features，compared with B-cell lymphoma，more aggressive， and lower chemotherapy sensitivity．In recent years,to explore high efficiency and light therapy adverse reactions chemotherapy，novel agents(such as gemcitabine ，pralatrexate and so on), targeted therapy combined with chemotherapy and high-dose chemotherapy combined with hematopoietic stem cell transplantation are studied for the treatment,and made some progress．

Key words:Lymphoma,T-cell,Chemotherapy