Journal of International Oncology››2012,Vol. 39››Issue (2): 143-148.
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MA Dong-Hua, ZHANG Liang, WANG Ya-Xu
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Abstract:The abnormal activation of phosphatidylinositol-3-kinase (PI3K)-protein kinase B (Akt) pathway has already been confirmed that it is closely related to the origin and development of various tumors. PI3K-Akt pathway plays an important role in development of colon cancer, it can regulate cell survival, proliferation, anti-apoptosis, cell cycle progression, etc. Furthermore, inhibition of this pathway may play a potential roll in oncotherapy.
MA Dong-Hua, ZHANG Liang, WANG Ya-Xu. The effect of phosphatidylinositol-3-kinase -protein kinase B signal pathway in colon cancer[J]. Journal of International Oncology, 2012, 39(2): 143-148.
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https://gjzlx.sdfmu.edu.cn/EN/Y2012/V39/I2/143
