Journal of International Oncology››2012,Vol. 39››Issue (7): 504-507.

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Reactive oxygen species and tumor therapy

ZHANG Hou-Li, CUI Shu-Xiang

  1. Pharmacological Laboratory, Institute of Materia Medica, Shandong Academy of Medical Sciences, Medicine and Life Science, Jinan Univesity, Institute of Materia Medica,Shandong Academy of Medical Sciences.Key Laboratory for Rave Disease of Shandong Procince, Jinan 250062, China
  • Online:2012-08-06Published:2012-08-06
  • Contact:CUI Shu-xiang,E-mail: sxccui@sina.com E-mail:sxccui@sina.com

Abstract:Oxidative stress can achieve the purpose of tumor therapy by accelerating the death of tumor cells. As a major molecule generated from the body's oxidative stress reaction, reactive oxygen species (ROS) exerts the antitumor efforts by promoting apoptosis, necrosis and autophagy. The drugs which could increase the level of ROS in cells have received more and more people's attention, and this provide a new research direction for the clinical treatment of tumors.

Key words:Reactive oxygen species,Neoplasms,Therapy