Journal of International Oncology››2013,Vol. 40››Issue (10): 748-751.

Previous ArticlesNext Articles

Application of attenuated salmonella in the gene treatment of tumor

LI Peng-Fei, SUN Jun-Zhong

  1. Department of Oncology, First Affiliated Hospital of General Hospital of PLA, Beijing 100039, China

  • Online:2013-10-08Published:2013-09-23
  • Contact:SUN Jun-zhong, E-mail: sjunzh07@163.com E-mail:sjunzh07@163.com

Abstract:Salmonella is a kind of intracellular invasive facultative anaerobe, maintaining its antigenicity after being attenuated. Now, it has been widely used as a transporter of DNA vaccines. Salmonella carrying related antigen gene can inhibit multiple tumors, and salmonella carrying repair gene has a clear repair effect for the organism injury after chemoradiotherapy.

Key words:Attenuated salmonella,Neoplasms,Vaccine carrier,Damage repairment