Journal of International Oncology››2013,Vol. 40››Issue (2): 120-122.

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Lung adenocarcinoma progression schema

YANG Zhen-Yu, FAN Zhi-Wen, ZHANG Lei

  1. Clinical Medical Specialty,Xiangya School of Medicine, Central South University , Changsha 410013, China
  • Online:2013-02-08Published:2013-01-25
  • Contact:Corresponding author: ZHANG Lei, E-mail: chinaray728@gmail.com E-mail:chinaray728@gmail.com

Abstract:Lung adenocarcinoma is usually thought to follow a linear multistep progression schema, that isprecancerouslesions progress to adenocarcinoma in situ, and progress to micro-invasive adenocarcinoma, eventually some lung adenocarcinoma happen diffusion. However, recent ?ndings reveal that this linear progression schema might not occur in all lung adenocarcinoma subtypes, and some subtypes show a kind ofnon-linearprogressionschema. The study of these two kinds of schemas can help for early detection of lung adenocarcinoma.

Key words:Lung neoplasms,DNA methylation,Etiology