Abstract:Toll-like receptor (TLR) is an important pattern recognition receptor (PRR) which participates in innate immunity and regulates adaptive immunity.TLRcan be expressedin immune cells and malignanttumors recognize conservative molecular structure, mediate response of inflammation, tissue injury and repair, which plays an important role in the process of tumor. Research results about some molecules and signal pathways of TLR demonstrate that it can act anti or pro-tumor dual functions, which has an extensive prospects in prevention and treatment of tumor.

Key words:Inflammation,Neoplasms,Epithelium,Toll-like receptor