Journal of International Oncology››2014,Vol. 41››Issue (2): 96-99.doi:10.3760/cma.j.issn.1673-422X.2014.02.006
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Huang Xuexiang, Yang Yu
Received:
2013-09-24Revised:
2013-12-04Online:
2014-02-08Published:
2014-01-26Contact:
Yang Yu E-mail:yangy@medmail.com.cnHuang Xuexiang, Yang Yu. Anti-tumor mechanisms of oleanolic acid[J]. Journal of International Oncology, 2014, 41(2): 96-99.
[1] Pollier J, Goossens A. Oleanolic acid[J]. Phytochemistr, 2012, 77: 10-15. [2] Zhou R, Zhang Z, Zhao L, et al. Inhibition of mTOR signaling by oleanolic acid contributes to its antitumor activity in osteosarcoma cells[J]. J Orthop Res, 2011, 29(6): 846-852. [3] Chu R, Zhao X, Griffin C, et al. Selective concomitant inhibition of mTORC1 and mTORC2 activity in estrogen receptor negative breast cancer cells by BN107 and oleanolic acid[J]. Int J Cancer, 2010, 127(5): 1209-1219. [4] Wang X, Bai H, Zhang X, et al. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERKp53mediated cell cycle arrest and mitochondrialdependent apoptosis[J]. Carcinogensis, 2013, 34(6): 1323-1330. [5] Pratheeshkumar P, Kuttan G. Oleanolic acid induces apoptosis by modulating p53, Bax, Bcl2 and caspase3 gene expression and regulates the activation of transcription factors and cytokine profile in B16F[J]. J Environ Pathol Toxicol Oncol, 2011, 30(1): 21-31. [6] Wei J, Liu M, Liu H, et al. Oleanolic acid arrests cell cycle and induces apoptosis via ROSmediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells[J]. J Appl Toxicol, 2013, 33(8): 756-765. [7] Yan SL, Huang CY, Wu ST, et al. Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines[J]. Toxicol In Vitro, 2010, 24(3): 842-848. [8] Feng L, AuYeung W, Xu YH, et al. Oleanolic acid from Prunella Vulgaris L. induces SPCA1 cell line apoptosis via regulation of Bax, Bad and Bcl2 expression[J]. Asian Pac J Cancer Prev, 2011, 12(2): 403-408. [9] Lúcio KA, Rocha Gda G, MonoRibeiro LC, et al. Oleanolic acid initiates apoptosis in nonsmall cell lung cancer cell lines and reduces metastasis of a B16F10 melanoma model in vivo[J]. PLoS One, 2011, 6(12): e28596. [10] Shan JZ, Xuan YY, Ruan SQ, et al. Proliferationinhibiting and apoptosisinducing effects of ursolic acid and oleanolic aicd on multidrug resistance cancer cells in vitro[J]. Chin J Integr Med, 2011, 17(8): 607-611. [11] Lin CC, Huang CY, Mong MC, et al. Antiangiogenic potential of three triterpenic acids in human liver cancer cells[J]. J Agric Food Chem, 2011, 59(2): 755-762. [12] Huang ZQ, Li HL, Sun LB, et al. Study on inhibitive effect of oleanolic acid on transplanted hepatocarcinoma in mice[J]. Medicinal Plant, 2011, 2(3): 52-54. |
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