Journal of International Oncology››2014,Vol. 41››Issue (3): 187-190.doi:10.3760/cma.j.issn.1673-422X.2014.03.008

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Epidemiology and pathogenesis research progress of cancer-related fatigue

CHEN Hong-Shan, WANG Yu-Dong, LIU Wei

  1. Department of Medical Oncology, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang 050011, China
  • Online:2014-03-08Published:2014-03-17
  • Contact:Liu Wei, E-mail: 524952149@qq.com E-mail:524952149@qq.com

Abstract:Cancer-related fatigue (CRF) is associated with tumor and (or) antitumor treatment, which has a high incidence and seriously affects the life quality of patients. The etiology of CRF involves psychology, physiology and social factors. There are various hypothesis of pathogenesis and the inflammatory system may play an important role in the generation and development of CRF. A variety of inflammatory cytokines such as IL-1β, IL-6, TNF-α, CRP are significantly correlated with CRF.

Key words:Neoplasms,Fatigue,Inflammation,Cytokines