Journal of International Oncology››2014,Vol. 41››Issue (5): 335-337.doi:10.3760/cma.j.issn.1673-422X.2014.05.005

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Epigenetics and nasopharyngeal carcinoma

Shen Jianjun, Zhang Hongyan

  1. Department of Radiation Oncology, Anhui Provincial Hospital, Hefei 230001, China
  • Received:2013-12-26Revised:2014-01-13Online:2014-05-08Published:2014-04-28
  • Contact:Zhang Hongyan E-mail:takemeparadise@163.com

Abstract:The etiology of nasopharyngeal carcinoma is still not very clear. Epigenetics is proved to play an important role in the occurrence and development of nasopharyngeal carcinoma (NPC). Detection of epigenetics can serve as molecular index of NPC, and it is advantageous to the prognosis and disease of NPC. Different intervention measures in the epigenetics can be used as a new treatment of NPC, as well as the development of new NPC radiotherapy sensitization agent and new drugs. Study of epigenetics changes in nasopharyngeal carcinoma provides a new idea for the diagnosis and treatment in NPC and so on.

Key words:Nasopharyngeal neoplasms,Heredity,Methylation