Journal of International Oncology››2015,Vol. 42››Issue (2): 141-143.doi:10.3760/cma.j.issn.1673-422X.2015.02.016

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Metastatic mechanisms of breast cancer

Zhong Jingmin, Zeng Liang

  1. Department of Pathology, Hunan Cancer Hospital & Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China
  • Online:2015-02-08Published:2015-02-02
  • Contact:Zeng Liang E-mail:zlxx03@qq.com

Abstract:Breast neoplasm shows high rate of incidence and mortality among females. Although there are a variety of treatments for breast neoplasm, breast neoplasm metastasis is still an intractable medical problem. At present, the related mechanisms of breast neoplasm metastasis are as follows: epithelialmesenchymal transition, dissolution of extracellular matrix, circulating tumor cells or disseminated tumor cells, tumor vessels and tumor microenvironment. Making clear of the related mechanisms of breast neoplasm metastasis has certain guiding significance for the prediction and treatmence of breast neoplasm metastasis.

Key words:Breast neoplasms,Neoplasm metastasis