Journal of International Oncology››2021,Vol. 48››Issue (8): 456-462.doi:10.3760/cma.j.cn371439-20210520-00088
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Received:2021-05-20Revised:2021-06-30Online:2021-08-08Published:2021-09-08
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| 串联器官 | 体积 (cm3) |
体积最大 剂量(Gy) |
最大点 剂量(Gy) |
不良事件 (≥3级) |
|---|---|---|---|---|
| 脑 | <10 | 12 | - | 放射性脑坏死 |
| <31a | 5 | - | ||
| 视觉通路 | <0.2 | 8 | 10 | 神经炎 |
| 晶体 | 10 | 白内障 | ||
| 耳蜗 | 9 | 听力减退 | ||
| 脑干(非脊髓) | <0.5 | 10 | 15 | 颅神经病变 |
| 脊髓 | <1.2 | 7 | 14 | 脊髓炎 |
| 脊髓分段(上下 各5~6 mm) |
<0.35 | 10 | 14 | 脊髓炎 |
| 马尾 | <5 | 14 | 16 | 神经炎 |
| 骶丛神经 | <5 | 14.4 | 16 | 神经病变 |
| 海马b | Dmean<3 | Dmax<9 |
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| 串联器官 | 体积(cm3) | 体积最大剂量 | 最大点剂量 | 不良事件(≥3级) |
|---|---|---|---|---|
| 视觉通路 | <0.2 | 15.3 Gy(5.1 Gy/Fx) | 17.4 Gy(5.8 Gy/Fx) | 神经炎 |
| 耳蜗 | 17.1 Gy(5.7 Gy/Fx) | 听力减退 | ||
| 脑干(非脊髓) | <0.5 | 18 Gy(6 Gy/Fx) | 23.1 Gy(7.7 Gy/Fx) | 颅神经病变 |
| 脊髓 | <1.2 | 12.3 Gy(4.1 Gy/Fx) | 脊髓炎 | |
| 脊髓分段(上下各5~6 mm) | <0.35 | 18 Gy(6 Gy/Fx) | 21.9 Gy(7.3 Gy/Fx) | 脊髓炎 |
| 马尾 | <5 | 21.9 Gy(7.3 Gy/Fx) | 24 Gy(8 Gy/Fx) | 神经炎 |
| 骶丛神经 | <5 | 22.5 Gy(7.5 Gy/Fx) | 24 Gy(8 Gy/Fx) | 神经病变 |
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| 串联器官 | 体积(cm3) | 体积最大剂量 | 最大点剂量 | 不良事件(≥3级) |
|---|---|---|---|---|
| 视觉通路 | <0.2 | 23 Gy(4.6Gy/Fx) | 25 Gy(5 Gy/Fx) | 神经炎 |
| 耳蜗 | 25 Gy(5 Gy/Fx) | 听力减退 | ||
| 脑干(非脊髓) | <0.5 | 23 Gy(4.6 Gy/Fx) | 31 Gy(6.2 Gy/Fx) | 颅神经病变 |
| 脊髓 | <1.2 | 14.5 Gy(2.9 Gy/Fx) | 脊髓炎 | |
| 脊髓分段(上下各5~6 mm) | <0.35 | 23 Gy(4.6 Gy/Fx) | 30 Gy(6 Gy/Fx) | 脊髓炎 |
| 马尾 | <5 | 30 Gy(6 Gy/Fx) | 32 Gy(6.4 Gy/Fx) | 神经炎 |
| 骶丛神经 | <5 | 30 Gy(6 Gy/Fx) | 32 Gy(6.4 Gy/Fx) | 神经病变 |
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