Abstract:Quantum dots (QDs), a kind of nanocrystal,are made fromII-VI or III-V group elements. It has been reported that compared with current conventional fluorescent markers, QDs have excellent optical properties such as strong fluorescence, photochemical stability and can be used for simultaneous multi-channel imaging. Meanwhile, as nanoparticle, QDs can be easily surface modified with a variety of biological molecular and can reach cancer cells easily by penetrating the tumor angiogenesis. Therefore, QDs have unique advantages in targeted real-time visual imaging of in vivo tumor and have great prospects in the individual diagnosis and treatment of tumor. However, the long-term biosafety after QDs into the body still needs further study.