Journal of International Oncology››2012,Vol. 39››Issue (1): 38-41.

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Primary esophageal small cell carcinoma

ZHANG Yu-Ling, WANG Jing, ZHANG Hao

  1. Department of Medical Record and Information, Cancer Hospital , Shantou University Medical College , Shantou 515041, China

  • Online:2012-01-08Published:2013-11-11
  • Contact:Corresponding author: ZHANG Hao, E-mail: haolabcancercenter@163.com E-mail:haolabcancercenter@163.com

Abstract:Primary esophageal small cell carcinoma (PESC) is a rare form of esophageal carcinoma which is with high degree of malignancy and early metastasis. Although the histological origin and etiology of PESC remains to largely unknown, one attractive viewpoint is that it derives fromoriginal pluripotent stem cellsof esophageal mucosa. PESC have both epithelium and neuroendocrine cellular features. Neuroendocrine biomarkers including NES and Syn have been used for identification of PESC.