Abstract:Hypoxia inducible factor-1(HIF-1) is usually highly expressed in tumor cells, and can promote tumor growth. HIF-1 is correlated with tumor condition, the diagnosis and the prognosis. Therefore, HIF-1 can be used for tumor treatment in the level of transcriprion, pro-transcriprion and target. It is possible to improve the treatment efficiency, and to lengthen patients lifespan.

Key words:Neoplasms,Hypoxia-inducible factor 1,Diagnosis,Therapy