Journal of International Oncology››2013,Vol. 40››Issue (10): 736-738.

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Carcinogenesis of cell cycle-related kinase

XIE Xu, TIAN Ye, TAN Guang

  1. DepartmentofHepatobiliarySurgery, First Affiliated Hospital of Dalian Medical University , Dalian 116011, china
  • Online:2013-10-08Published:2013-09-23
  • Contact:TAN Guang, E-mail: tanguang009@sina.com E-mail:tanguang009@sina.com

Abstract:Cell cycle-related kinase (CCRK) as a novel CDK-activating kinase plays a significant role in cell cycle regulation. Related studies confirm that CCRK is overexpressedin varioustumors, and is associated withpoor prognosis of the patients, which indicates that CCRK takes part in the generation and development of the tumor.

Key words:Gene expression regulation, neoplastic,Cyclin-dependent kinases,Cell cycle