Journal of International Oncology››2014,Vol. 41››Issue (5): 357-360.doi:10.3760/cma.j.issn.1673-422X.2014.05.012
Previous ArticlesNext Articles
Li Minmin, Bi Xiang, Wang Zhehai
Received:
2013-12-23Revised:
2014-01-10Online:
2014-05-08Published:
2014-04-28Contact:
Wang Zhehai E-mail:badgood007@126.comLi Minmin, Bi Xiang, Wang Zhehai. Acquired resistance to anti-EGFR antibodies in metastatic colorectal cancer[J]. Journal of International Oncology, 2014, 41(5): 357-360.
[1] Bardelli A, Jnne PA. The road to resistence: EGFR mutation and cetuximab[J]. Nat Med, 2012, 18(2):199-200. [2] Montagut C, Dalmases A, Bellosillo B, et al. Identification of a mutation in the extracellular domain of the epidermal growth factor receptor conferring cetuximab resistence in colorectal cancer[J]. Nat Med, 2012, 18(2):221-223. [3] Wheeler DL, Huang S, Kruser TJ, et al. Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members[J]. Oncogene, 2008, 27(28):3944-3956. [4] Lu Y, Li X, liang K, et al. Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistence escaping treatment by the antiEGFR monoclonal antibody cetuximab[J]. Cancer Res, 2007, 67(17):8240-8247. [5] Misale S, Yaeger R, Hobor S, et al. Emergence of KRAS mutations and acquired resistance to antiEGFR therapy in colorectal cancer[J]. Nature, 2012, 486(7404):532-536. [6] Diaz LA Jr, Williams RT, Wu J, et al. The molecular evolution of acquiredresistance to targeted EGFR blockade in colorectal cancers[J]. Nature, 2012, 486(7404):537-540. [7] Brand TM, Iida M, Wheeler DL. Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab[J]. Cancer Biol Ther, 2011, 11(9):777792. [8] Ciardiello F, Bianco R, Caputo R. Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor,in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy[J]. Clin Cancer Res, 2004, 10(2):784-793. [9] Vallbhmer D, Zhang W, Gordon M, et al. Molecular determinants of cetuximab efficacy[J]. J Clin Oncol, 2005, 23(15):3536-3544. [10] Li C, Iida M, Dunn EF, et al. Nuclear EGFR contributes to acquired resistence to cetuximab[J]. Oncogene, 2009, 28(43):3801-3813. [11] OliverasFerraros C, Massaguer VallLlovera A, Carrion Salip D, et al. Evolution of the predictive markers amphiregulin and epiregulin mRNA during long term cetuximab treatment of KRAS wild type tumor cells[J]. Invest New Drugs, 2012, 30(2):846-852. [12] Kim SM, Kim JS, Kim JH, et al. Acquired resistance to cetuximab is mediated by increased PTEN instability and lead crossresistance to gefitinib in HCC827 NSCLC cells[J]. Cancer Lett, 2010, 296(2):150159. [13] Wheeler DL, Lida M, Kruser TJ, et al. Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab[J]. Cancer Biol Ther, 2009, 8(8):696-703. [14] Santini D, Vincenzi B, Addeo R, et al. Cetuximab rechallenge in metastatic colorectal cancer patients: how to come away from acquired resistance?[J]. Ann Oncol, 2012, 23(9):2313-2318. [15] Sobrero AF, Maurel J, Fehrenbacher L, et al. EPIC: phase Ⅲ trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer[J]. J Clin Oncol, 2008, 26(14):2311-2319. [16] Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecanrefractory metastatic colorectal cancer[J]. N Engl J Med, 2004, 351(4):337-334. [17] Matar P, Rojo F, Cassia R. Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMGC225): superiority over singleagent receptor targeting[J]. Clin Cancer Res, 2004, 10(19):6487-6501. [18] Dunn EF, Iida M, Myers RA, et al. Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab[J]. Oncogene, 2011, 30(5):561-574. [19] Garrett JT, Arteaga CL. Resistance to HER2directed antibodies and tyrosine kinase inhibitors: mechanisms and clinical implications[J]. Cancer Biol Ther, 2011,11(9):793-800. [20] Grothey A, Van Cutsem E, Sobrero A, et al. Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international,multicentre, randomised, placebocontrolled, phase 3 trial[J]. Lancet, 2013, 381(9863):303-312. |
[1] | Zhang Rui, Chu Yanliu.Research progress of colorectal cancer risk assessment models based on FIT and gut microbiota[J]. Journal of International Oncology, 2024, 51(6): 370-375. |
[2] | Gao Fan, Wang Ping, Du Chao, Chu Yanliu.Research progress on intestinal flora and non-surgical treatment of the colorectal cancer[J]. Journal of International Oncology, 2024, 51(6): 376-381. |
[3] | Wang Junyi, Hong Kaibin, Ji Rongjia, Chen Dachao.Effect of cancer nodules on liver metastases after radical resection of colorectal cancer[J]. Journal of International Oncology, 2024, 51(5): 280-285. |
[4] | Yang Zhi, Lu Yiqiao, Gu Huayan, Ding Jialing, Guo Guilong.Research progress of tumor microenvironment mediated drug resistance in targeted therapy of breast cancer[J]. Journal of International Oncology, 2024, 51(4): 235-238. |
[5] | Gong Yan, Chen Honglei.Research progress on the mechanism of microRNA regulation of cisplatin resistance in ovarian cancer[J]. Journal of International Oncology, 2024, 51(3): 186-190. |
[6] | Sun Guobao, Yang Qian, Zhuang Qingchun, Gao Binbin, Sun Xiaogang, Song Wei, Sha Dan.Research progress on the histopathological growth patterns of colorectal liver metastasis[J]. Journal of International Oncology, 2024, 51(2): 114-118. |
[7] | Liu Debao, Sun Ziwen, Lu Shoutang, Xu Haidong.Expression and clinical significance of ASB6 in colorectal cancer tissues[J]. Journal of International Oncology, 2023, 50(8): 470-474. |
[8] | An Rong, Liu Meihua, Wang Peichen, Wang Xiaohui.Research progress of Nrf2 in ovarian cancer[J]. Journal of International Oncology, 2023, 50(8): 493-497. |
[9] | Wang Wende, Zeng De.Research progress on the mechanism of endocrine therapy resistance for breast cancer[J]. Journal of International Oncology, 2023, 50(6): 352-356. |
[10] | Chen Zhuo, Tao Jun, Chen Lin, Ke Jing.Value of detection of peripheral blood miR-194 combined with fecal miR-143 in the clinical screening of colorectal cancer[J]. Journal of International Oncology, 2023, 50(5): 268-273. |
[11] | Huang Zhen, Zhang Caiyutian, Ke Shaobo, Shi Wei, Zhao Wensi, Chen Yongshun.Construction of postoperative prognosis model for patients with colorectal cancer[J]. Journal of International Oncology, 2023, 50(3): 157-163. |
[12] | Xu Liangfu, Li Yuanfei.Research progress on tumor microenvironment and immune combination therapy of MSS colorectal cancer[J]. Journal of International Oncology, 2023, 50(3): 186-190. |
[13] | Liu Yujie, Zhao Zhiqiang, Wang Zicheng.Levels and diagnostic value of TOP2A and ERBB2 in peripheral blood mononuclear cells of patients with early colorectal cancer[J]. Journal of International Oncology, 2023, 50(12): 717-722. |
[14] | Tao Hong, Yin Hong, Luo Hong, Tao Jiayu.Potential strategies for targeting tumor-associated macrophages to enhance the efficacy of immune checkpoint inhibitors for colorectal cancer[J]. Journal of International Oncology, 2023, 50(11): 683-687. |
[15] | Liu Xiaojie, Huang Junxing.Research progress of NADPH oxidase 2 in malignant tumors[J]. Journal of International Oncology, 2023, 50(10): 618-621. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||