lijunshenghd@163.com。
"],"authorList":[{"zuoZheDiZhiL_cn":["东南大学附属中大医院,普外科,江苏 南京 210009 ;"],"deceased":false,"name_cn":"张海峰","zuoZheDiZhiL_en":["Department of General Surgery, Zhongda Hospital Southeast University,Nanjing 210009,China ;"],"name_en":"Haifeng ZHANG"},{"zuoZheDiZhiL_cn":["东南大学附属中大医院,肿瘤科,江苏 南京 210009 ;"],"deceased":false,"name_cn":"郑士亚","zuoZheDiZhiL_en":["Department of Oncology, Zhongda Hospital Southeast University,Nanjing 210009,China ;"],"name_en":"Shiya ZHENG"},{"zuoZheDiZhiL_cn":["东南大学附属中大医院,普外科,江苏 南京 210009 ;"],"deceased":false,"name_cn":"程韬","zuoZheDiZhiL_en":["Department of General Surgery, Zhongda Hospital Southeast University,Nanjing 210009,China ;"],"name_en":"Tao CHENG"},{"zuoZheDiZhiL_cn":["东南大学附属中大医院,普外科,江苏 南京 210009 ;"],"deceased":false,"name_cn":"邵翔宇","zuoZheDiZhiL_en":["Department of General Surgery, Zhongda Hospital Southeast University,Nanjing 210009,China ;"],"name_en":"Xiangyu SHAO"},{"zuoZheDiZhiL_cn":["东南大学附属中大医院,普外科,江苏 南京 210009 ;"],"deceased":false,"name_cn":"李俊生","email":"lijunshenghd@163.com","zuoZheDiZhiL_en":["Department of General Surgery, Zhongda Hospital Southeast University,Nanjing 210009,China ;"],"name_en":"Junsheng LI"}],"affList_en":["1.Department of General Surgery, Zhongda Hospital Southeast University,Nanjing 210009,China
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生物材料在组织修复与再生领域中扮演着至关重要的角色,其应用可显著提高临床治疗效果,并改善患者预后。智能响应性生物材料是一类能够对外界刺激如温度、pH值、光照、电场、磁场以及生物分子等做出响应并产生相应变化的材料,在组织工程中展现出巨大的应用前景。本文将对智能响应性生物材料促进组织修复机制及智能响应机制作一综述,并进一步分析智能响应性生物材料在组织修复与再生过程中的挑战和未来发展方向。

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智能响应性生物材料在组织修复与再生中的应用进展

张海峰, 郑士亚, 程韬, 邵翔宇, 李俊生

betway必威登陆网址 (betway.com )学报››2024, Vol. 45››Issue (12): 752-758.

PDF(527 KB)
PDF(527 KB)
betway必威登陆网址 (betway.com )学报 ›› 2024, Vol. 45 ›› Issue (12) : 752-758. DOI: 10.3969/j.issn.2097-0005.2024.12.009
综述

智能响应性生物材料在组织修复与再生中的应用进展

    作者信息 +

    Advances in the application of smart responsive biomaterials in tissue repair and regeneration

      Author information +
      文章历史 +

      摘要

      生物材料在组织修复与再生领域中扮演着至关重要的角色,其应用可显著提高临床治疗效果,并改善患者预后。智能响应性生物材料是一类能够对外界刺激如温度、pH值、光照、电场、磁场以及生物分子等做出响应并产生相应变化的材料,在组织工程中展现出巨大的应用前景。本文将对智能响应性生物材料促进组织修复机制及智能响应机制作一综述,并进一步分析智能响应性生物材料在组织修复与再生过程中的挑战和未来发展方向。

      Abstract

      In the field of tissue regeneration and repair, biomaterials are essential, and their use can enhance patient outcomes and prognoses. A class of materials known as smart-responsive biomaterials is able to react and change in response to various environmental stimuli, including light, temperature, pH, electric and magnetic fields, and biomolecules. Because of these materials' special qualities, tissue engineering could benefit greatly from their use. An overview of smart response and smart responsive biomaterials' mechanism for encouraging tissue healing will be provided in this study, along with an analysis of the difficulties and potential applications of smart responsive biomaterials in tissue regeneration and repair.

      关键词

      智能响应性生物材料/组织修复/再生医学

      Key words

      smart responsive biomaterials/tissue repair/regenerative medicine

      引用本文

      导出引用
      张海峰, 郑士亚, 程韬, 邵翔宇, 李俊生.智能响应性生物材料在组织修复与再生中的应用进展[J]. betway必威登陆网址 (betway.com )学报. 2024, 45(12): 752-758 https://doi.org/10.3969/j.issn.2097-0005.2024.12.009
      Haifeng ZHANG, Shiya ZHENG, Tao CHENG, Xiangyu SHAO, Junsheng LI.Advances in the application of smart responsive biomaterials in tissue repair and regeneration[J]. Journal of ShanDong First Medical University&ShanDong Academy of Medical Sciences. 2024, 45(12): 752-758 https://doi.org/10.3969/j.issn.2097-0005.2024.12.009

      参考文献

      1 Gurtner GC, Werner S, Barrandon Y, et al. Wound repair and regeneration[J].Nature2008453(7193): 314.
      2 戴建武. 引导组织再生智能生物材料的转化研究[J].生命科学201628(8): 907.
      3 曹谊林, 刘伟, 张文杰, 等. 组织工程研究进展[J].上海交通大学学报(医学版)201232(9): 1241.
      4 张海璇, 孟旬, 李平. 光和温度刺激响应型材料[J].化学进展200820(5): 657.
      5 柴梅, 黄琛琛, 夏胜男, 等. 铸瓷粘结桥修复深覆(牙合)伴单颗前牙缺失的临床效果[J].betway必威登陆网址 (betway.com )学报202445(6): 326.
      6 Panayi AC, Orgill DP. Current use of biological scaffolds in plastic surgery[J].Plast Reconstr Surg2019143(1): 209.
      7 Yannas IV, Lee E, Orgill DP, et al. Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin[J].Proc Natl Acad Sci U S A198986(3): 933.
      8 Groeber F, Holeiter M, Hampel M, et al. Skin tissue engineering -- in vivo andin vitroapplications[J].Clin Plast Surg201239(1): 33.
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