目的

探讨双水平正压通气(BiPAP)治疗中-重度毛细支气管炎的疗效。

方法

回顾性分析2016年11月—2020年3月betway必威登陆网址 第二附属医院儿内科收治的120例中-重度毛细支气管炎患儿的临床资料,根据治疗措施,将患儿随机分为治疗组(BiPAP组)和对照组,每组60例。分析治疗前及治疗24 h后动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、乳酸、呼吸频率(RR)、心率(HR)、住院时间及气管插管率等指标。

结果

治疗24 h后,BiPAP治疗组血气指标及心率和呼吸的改善均较常规治疗组明显,差异均有统计学意义(P < 0.05);两组患儿气管插管机械通气率、入住PICU的时间的差异均具有统计学意义(P < 0.05)。

结论

早期应用BiPAP治疗中-重度毛细支气管炎,能有效改善患儿临床症状,纠正血气指标,缩短住院时间。

","endNoteUrl_en":"http://xuebao.sdfmu.edu.cn/EN/article/getTxtFile.do?fileType=EndNote&id=155","reference":"
1 史瑞明,刁敏,李成尧.毛细支气管炎治疗新观点[J]. 中国实用儿科杂志,2019,34 (9):749.
2 罗健.重症毛细支气管炎的治疗[J]. 中国实用儿科杂志,2019,34(9):742.
3 《中华儿科杂志》编辑委员会,中华医学会儿科学分会呼吸学组.毛细支气管炎诊断、治疗与预防专家共识(2014年版)[J]. 中华儿科杂志, 2015,53(3):168.
4 刘军,谢正德.毛细支气管炎的病原学及临床流行病学特征[J]. 中国实用儿科杂志,2019,34(9):729.
5 史瑞鹤,刘恩梅.持续气道正压通气在重症毛细支气管炎中的应用[J]. 临床儿科杂志,2015,33(6):588.
6 杨新利,崔立云,米青,等.加温湿化高流量鼻导管吸氧治疗儿童毛细支气管炎的临床研究[J]. 中国小儿急救医学,2017,24(6):430.
7 曾健生,钱素云.促进儿童无创正压通气的临床应用[J]. 中华儿科杂志,2017,55(5):321.
8 马力,杨海波,温晓红.双水平正压通气在早产儿呼吸支持中的应用进展[J]. 临床儿科杂志,2018,36(9):707.
9 Amaddeo A,Frapin A,Fauroux B.Long-term non-invasive ventilation in children [J]. Lancet RespirMed,2016,4(12):999.
10 蔡琳,李晓东,田青.经鼻双水平正压通气治疗早产儿呼吸窘迫综合征临床疗效[J]. 中国新生儿科杂志,2015,30(5):361.
11 Essouri S,Durand P,Chevret,et al.Optimal level of nasal continuous positive airway pressure insevere viral bronchiolitis[J]. Intensive Care Med, 2011,37(12):2002.
12 中华医学会儿科学分会急救学组,《中华儿科杂志》编辑委员会.儿童双水平气道正压通气临床应用专家共识[J]. 中华儿科杂志,2017,55(5):324.
13 贾系群,张楠,唐玉峰,等.尽早应用经鼻持续正压通气治疗中重度毛细支气管炎的疗效[J]. 中华实用儿科临床杂志,2019,34(16):1259.
14 吴伟,王自财,周曙明.双水平正压通气治疗小儿重症毛细支气管炎的效果观察[J]. 中国当代医药,2015,22(13): 3720.
15 《中华结核和呼吸杂志》编辑委员会,中华医学会呼吸病学分会呼吸生理与重症监护学组.无创正压通气临床应用专家共识[J]. 中华结核和呼吸杂志,2009,32(2): 86.
","bibtexUrl_cn":"//www.pitakata.com/xuebao/CN/article/getTxtFile.do?fileType=BibTeX&id=155","articleType":"research-article","abstractUrl_en":"http://xuebao.sdfmu.edu.cn/EN/10.3969/j.issn.2097-0005.2021.08.012","qi":"8","id":155,"nian":2021,"bianHao":"1632972981994-1473312154","zuoZheEn_L":"Gongli Li, Minmin Duan, Delei Zhang","juanUrl_en":"http://xuebao.sdfmu.edu.cn/EN/Y2021","clcIndexList_en":[{"code":"R725.6","text":""}],"shouCiFaBuRiQi":"2021-09-28","qiShiYe":"610","received":"2021-02-02","qiUrl_cn":"//www.pitakata.com/xuebao/CN/Y2021/V42/I8","lanMu_cn":"临床研究","pdfSize":"417","zuoZhe_CN":"李公利(), 段敏敏, 张德磊","risUrl_cn":"//www.pitakata.com/xuebao/CN/article/getTxtFile.do?fileType=Ris&id=155","title_cn":"双水平正压通气治疗中-重度毛细支气管炎的临床疗效","doi":"10.3969/j.issn.2097-0005.2021.08.012","jieShuYe":"612","keywordList_en":["bronchiolitis","bi-level positive airway pressure(BiPAP)","infant"],"endNoteUrl_cn":"//www.pitakata.com/xuebao/CN/article/getTxtFile.do?fileType=EndNote&id=155","zhaiyao_en":"Objective

To investigate the clinical efficacy of bi-level positive airway pressure(BiPAP) in moderate to severe capillary bronchiotis.

Methods

120 children with moderate to severe capillary bronchiotis in The Second Affiliated Hospital of Shandong First Medical University from November 2016 to March 2019 were selected and divided into treatment group(n = 60) and conventional group(n = 60). Arterial blood gas analysis, lactic acid,the clinical manifestations,the proportion of need forendobronchial intubation and time in PICU were recorded and compared.

Results

After 24 hours treatment, arterial blood gas analysis,heart rate and respiratory rate were greatly improved in cases with BiPAP than those in cases with conventional oxygen(P < 0.05). the differences in needing endobronchial intubation rate and time in PICU were statistically significant between the 2 groups(P < 0.05).

Conclusion

The early use of BiPAP for eligible patients can improve clinical symptoms and signs of moderate to severe capillary bronchiotis in children, rectify blood gas,and can shorten length of hospital stay.

","bibtexUrl_en":"http://xuebao.sdfmu.edu.cn/EN/article/getTxtFile.do?fileType=BibTeX&id=155","abstractUrl_cn":"http://xuebao.sdfmu.edu.cn/CN/10.3969/j.issn.2097-0005.2021.08.012","zuoZheCn_L":"李公利, 段敏敏, 张德磊","juanUrl_cn":"http://xuebao.sdfmu.edu.cn/CN/Y2021","lanMu_en":"Clinical Researches","clcIndexList_cn":[{"code":"R725.6","text":""}],"qiUrl_en":"http://xuebao.sdfmu.edu.cn/EN/Y2021/V42/I8","zuoZhe_EN":"Gongli Li(), Minmin Duan, Delei Zhang","risUrl_en":"http://xuebao.sdfmu.edu.cn/EN/article/getTxtFile.do?fileType=Ris&id=155","title_en":"Clinical medical research of bi-level positive airyway pressure in moderate to severe capillary bronchiotis","hasPdf":"true"},"authorNotes_cn":["李公利,副主任医师,硕士,主要从事临床儿科工作,E-mail:kuaileerke@126.com。"],"authorList_en":[{"zuoZheDiZhiL_cn":["betway必威登陆网址 第二附属医院儿科,山东 泰安 271000 ;"],"deceased":false,"name_cn":"李公利","email":"kuaileerke@126.com","zuoZheDiZhiL_en":["Department of Pediatrics,The Second Affiliated Hospital of Shandong First Medical University,Taian 271000,China ;"],"name_en":"Gongli Li"},{"zuoZheDiZhiL_cn":["betway必威登陆网址 第二附属医院儿科,山东 泰安 271000 ;"],"deceased":false,"name_cn":"段敏敏","zuoZheDiZhiL_en":["Department of Pediatrics,The Second Affiliated Hospital of Shandong First Medical University,Taian 271000,China ;"],"name_en":"Minmin Duan"},{"zuoZheDiZhiL_cn":["betway必威登陆网址 第二附属医院儿科,山东 泰安 271000 ;"],"deceased":false,"name_cn":"张德磊","zuoZheDiZhiL_en":["Department of Pediatrics,The Second Affiliated Hospital of Shandong First Medical University,Taian 271000,China ;"],"name_en":"Delei Zhang"}]}">

双水平正压通气治疗中-重度毛细支气管炎的临床疗效

李公利, 段敏敏, 张德磊

betway必威登陆网址 (betway.com )学报››2021, Vol. 42››Issue (8): 610-612.

PDF(417 KB)
PDF(417 KB)
betway必威登陆网址 (betway.com )学报 ›› 2021, Vol. 42 ›› Issue (8) : 610-612. DOI: 10.3969/j.issn.2097-0005.2021.08.012
临床研究

双水平正压通气治疗中-重度毛细支气管炎的临床疗效

    作者信息 +

    Clinical medical research of bi-level positive airyway pressure in moderate to severe capillary bronchiotis

      Author information +
      文章历史 +

      摘要

      目的

      探讨双水平正压通气(BiPAP)治疗中-重度毛细支气管炎的疗效。

      方法

      回顾性分析2016年11月—2020年3月betway必威登陆网址 第二附属医院儿内科收治的120例中-重度毛细支气管炎患儿的临床资料,根据治疗措施,将患儿随机分为治疗组(BiPAP组)和对照组,每组60例。分析治疗前及治疗24 h后动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、乳酸、呼吸频率(RR)、心率(HR)、住院时间及气管插管率等指标。

      结果

      治疗24 h后,BiPAP治疗组血气指标及心率和呼吸的改善均较常规治疗组明显,差异均有统计学意义(P< 0.05);两组患儿气管插管机械通气率、入住PICU的时间的差异均具有统计学意义(P< 0.05)。

      结论

      早期应用BiPAP治疗中-重度毛细支气管炎,能有效改善患儿临床症状,纠正血气指标,缩短住院时间。

      Abstract

      Objective

      To investigate the clinical efficacy of bi-level positive airway pressure(BiPAP) in moderate to severe capillary bronchiotis.

      Methods

      120 children with moderate to severe capillary bronchiotis in The Second Affiliated Hospital of Shandong First Medical University from November 2016 to March 2019 were selected and divided into treatment group(n= 60) and conventional group(n= 60). Arterial blood gas analysis, lactic acid,the clinical manifestations,the proportion of need forendobronchial intubation and time in PICU were recorded and compared.

      Results

      After 24 hours treatment, arterial blood gas analysis,heart rate and respiratory rate were greatly improved in cases with BiPAP than those in cases with conventional oxygen(P< 0.05). the differences in needing endobronchial intubation rate and time in PICU were statistically significant between the 2 groups(P< 0.05).

      Conclusion

      The early use of BiPAP for eligible patients can improve clinical symptoms and signs of moderate to severe capillary bronchiotis in children, rectify blood gas,and can shorten length of hospital stay.

      关键词

      毛细支气管炎/双水平正压通气/婴幼儿

      Key words

      bronchiolitis/bi-level positive airway pressure(BiPAP)/infant

      引用本文

      导出引用
      李公利, 段敏敏, 张德磊.双水平正压通气治疗中-重度毛细支气管炎的临床疗效[J]. betway必威登陆网址 (betway.com )学报. 2021, 42(8): 610-612 https://doi.org/10.3969/j.issn.2097-0005.2021.08.012
      Gongli Li, Minmin Duan, Delei Zhang.Clinical medical research of bi-level positive airyway pressure in moderate to severe capillary bronchiotis[J]. Journal of ShanDong First Medical University&ShanDong Academy of Medical Sciences. 2021, 42(8): 610-612 https://doi.org/10.3969/j.issn.2097-0005.2021.08.012
      中图分类号: R725.6

      参考文献

      1 史瑞明,刁敏,李成尧.毛细支气管炎治疗新观点[J]. 中国实用儿科杂志,2019,34 (9):749.
      2 罗健.重症毛细支气管炎的治疗[J]. 中国实用儿科杂志,2019,34(9):742.
      3 《中华儿科杂志》编辑委员会,中华医学会儿科学分会呼吸学组.毛细支气管炎诊断、治疗与预防专家共识(2014年版)[J]. 中华儿科杂志, 2015,53(3):168.
      4 刘军,谢正德.毛细支气管炎的病原学及临床流行病学特征[J]. 中国实用儿科杂志,2019,34(9):729.
      5 史瑞鹤,刘恩梅.持续气道正压通气在重症毛细支气管炎中的应用[J]. 临床儿科杂志,2015,33(6):588.
      6 杨新利,崔立云,米青,等.加温湿化高流量鼻导管吸氧治疗儿童毛细支气管炎的临床研究[J]. 中国小儿急救医学,2017,24(6):430.
      7 曾健生,钱素云.促进儿童无创正压通气的临床应用[J]. 中华儿科杂志,2017,55(5):321.
      8 马力,杨海波,温晓红.双水平正压通气在早产儿呼吸支持中的应用进展[J]. 临床儿科杂志,2018,36(9):707.
      9 Amaddeo A,Frapin A,Fauroux B.Long-term non-invasive ventilation in children [J]. Lancet RespirMed,2016,4(12):999.
      10 蔡琳,李晓东,田青.经鼻双水平正压通气治疗早产儿呼吸窘迫综合征临床疗效[J]. 中国新生儿科杂志,2015,30(5):361.
      11 Essouri S,Durand P,Chevret,et al.Optimal level of nasal continuous positive airway pressure insevere viral bronchiolitis[J]. Intensive Care Med, 2011,37(12):2002.
      12 中华医学会儿科学分会急救学组,《中华儿科杂志》编辑委员会.儿童双水平气道正压通气临床应用专家共识[J]. 中华儿科杂志,2017,55(5):324.
      13 贾系群,张楠,唐玉峰,等.尽早应用经鼻持续正压通气治疗中重度毛细支气管炎的疗效[J]. 中华实用儿科临床杂志,2019,34(16):1259.
      14 吴伟,王自财,周曙明.双水平正压通气治疗小儿重症毛细支气管炎的效果观察[J]. 中国当代医药,2015,22(13): 3720.
      15 《中华结核和呼吸杂志》编辑委员会,中华医学会呼吸病学分会呼吸生理与重症监护学组.无创正压通气临床应用专家共识[J]. 中华结核和呼吸杂志,2009,32(2): 86.

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