关键词: 肺孤立小结节, 多层螺旋CT, 低剂量扫描, 良恶性鉴别

Abstract: Objective: To investigate the value of low-dose multi-slice spiral CT (MSCT) in the differential diagnosis of benign and malignant solitary pulmonary nodules (SPN).Methods: 68 patients with SPN who were treated in Anyang People's Hospital from November 2018 to November 2020 were selected as the research objects.All patients received MSCT to confirm the benign and malignant nodules, and MSCT low-dose scans in the diagnostic value of SPN benign and malignant differentiation were analyzed with surgical pathology as the "gold standard".Results: With the use of the pathological results as the "gold standard", the accuracy of MSCT scanning in the differentiation of SPN benign and malignant was 92.65%, the sensitivity was 93.18%, and the specificity was 91.67%, which was in good agreement with the pathological results (Kappa=0.841). The typical imaging features of malignant nodules were irregular or lobed edges, blurring, and uniform internal structure; benign nodules had clear edges and most of them were accompanied by calcification. The imaging features of the two groups were compared, and the difference was statistically significant (P <0.05). Conclusion: The low-dose MSCT scan is of high value in the differential diagnosis of benign and malignant SPN. It can be effectively differentiated by the imaging features of the edges and internal structure of the two, and has high clinical application value.

Key words: solitary pulmonary nodules, multi-slice spiral CT, low-dose scanning, differentiation of benign and malignant