放射性肠炎临床诊疗新进展

国际肿瘤学杂志››2023,Vol. 50››Issue (1): 28-32.doi:10.3760/cma.j.cn371439-20220930-00005

马辰莺¹, 赵晶¹, 徐晓婷¹, 秦颂兵¹, 周菊英^1,²()

¹苏州大学附属第一医院放疗科，苏州 215006
²放射医学与辐射防护国家重点实验室（苏州大学），苏州 215123

收稿日期:2022-09-30修回日期:2022-12-02出版日期:2023-01-08发布日期:2023-03-16
通讯作者:周菊英 E-mail:zhoujuyingsy@163.com
基金资助:
国家自然科学基金(81602792);国家自然科学基金(81602802);苏州大学放射医学与辐射防护国家重点实验室资助项目(GZK1202101);苏州市科技发展计划(SS201628);苏州市科技发展计划(KJXW2020008);苏州大学附属第一医院自然科学基金博习培育计划(BXQN202107)

Advances in clinical diagnosis and treatment of radiation enteritis

Ma Chenying¹, Zhao Jing¹, Xu Xiaoting¹, Qin Songbing¹, Zhou Juying^1,²()

¹Department of Radiation Oncology， the First Affiliated Hospital of Soochow University， Suzhou 215006， China
²State Key Laboratory of Radiation Medicine and Protection， Soochow University， Suzhou 215123， China

Received:2022-09-30Revised:2022-12-02Online:2023-01-08Published:2023-03-16
Contact:Zhou Juying E-mail:zhoujuyingsy@163.com
Supported by:
National Natural Science Foundation of China(81602792);National Natural Science Foundation of China(81602802);Project of State Key Laboratory of Radiation Medicine and Protection， Soochow University(GZK1202101);Suzhou Science and Technology Development Plan Project(SS201628);Suzhou Science and Technology Development Plan Project(KJXW2020008);BOXI Natural Science Cultivation Foundation of China of the First Affiliated Hospital of Soochow University(BXQN202107)

摘要/Abstract

摘要：

小肠胶囊内镜与双气囊小肠镜检查逐渐成为临床诊断放射性肠炎（RE）的新手段，尤其是对异常肠道组织的诊断。靶向活检或介入治疗有望实现RE的精准治疗。而筛选生物样本中的分子标志物也成为RE诊断新方向。粪便微生物群移植已成为具有前景的RE治疗手段之一，此外基于传统中草药、靶问细胞死亡以及组学分析的机制研究为RE的诊疗提供了新策略。

关键词:盆腔肿瘤,胃肠疾病,放射性肠炎

Abstract:

Small bowel capsule endoscopy and double-balloon enteroscopy have become new methods for clinical diagnosis of radiation enteritis （RE）， especially for abnormal intestinal tissue. Targeted biopsy or interventional therapy is expected to achieve precision treatment of RE. The screening of molecular markers in biological samples has also become a new direction for RE diagnosis. Fecal microbiota transplantation has become one of the promising treatments for RE. In addition， mechanism studies based on traditional Chinese medicine， targeted cell death， and omics analysis provide rich strategies for the diagnosis and treatment of RE.

Key words:Pelvic neoplasms,Gastrointestinal diseases,Radiation enteritis

马辰莺, 赵晶, 徐晓婷, 秦颂兵, 周菊英. 放射性肠炎临床诊疗新进展[J]. 国际肿瘤学杂志, 2023, 50(1): 28-32.

Ma Chenying, Zhao Jing, Xu Xiaoting, Qin Songbing, Zhou Juying. Advances in clinical diagnosis and treatment of radiation enteritis[J]. Journal of International Oncology, 2023, 50(1): 28-32.

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