国际肿瘤学杂志››2014,Vol. 41››Issue (10): 757-760.doi:10.3760/cma.j.issn.1673-422X.2014.10.012

• 综述 •上一篇下一篇

局限期小细胞肺癌放疗现状及研究进展

韩丹, 李宝生

  1. 250117济南 山东省肿瘤防治研究院放疗六科 betway.com 济南大学医学与生命科学学院

  • 出版日期:2014-10-29发布日期:2014-10-11
  • 通讯作者:李宝生,E-mail:baoshli@yahoo.com E-mail:baoshli@yahoo.com

Current status and advances of radiotherapy for limited-disease small cell lung cancer

HAN Dan, LI Bao-Sheng

  1. SixthDepartment ofRadiation Oncology,Shandong Cancer Hospital, School of Medicine and Life Science,University of Ji’nan-Shandong Academy of Medical Sciences,Ji’nan250117, China

  • Online:2014-10-29Published:2014-10-11
  • Contact:LI Bao-Sheng E-mail:baoshli@yahoo.com

摘要:小细胞肺癌中大约30%~40%属于局限期。大量研究已经证明胸部放疗联合同步化疗可以改善局部控制率及总生存率,是目前局限期小细胞肺癌的标准治疗模式,预防性脑照射也被证实可以改善小细胞肺癌的预后。目前认为放疗应在化疗早期加入,个体化制定合适的放疗靶区,放疗方案推荐超分割方式或常规分割方式。

关键词:

margin-bottom: 0pt">font-family: '宋体',mso-spacerun: 'yes'">癌,小细胞,放射疗法,局限期

Abstract:About30% ~40% ofsmallcelllungcancer(SCLC)patientsbelongtolimiteddisease (LD).Inthesettingoflimiteddiseasesmallcelllungcancer(LDSCLC),thecombinationofthoracicradio therapy(TRT)withchemotherapyisthestandardtreatmentforLDSCLCwithimprovedsurvivalandlocalcon trol.ItisproventhatprophylacticcranialirradiationcanimprovetheprognosisofpatientswithSCLC.Radio therapyshouldjoinintheearlychemotherapyandindividualizedformulateappropriatetargetvolume.Radiation schemesofconventionalfractionationorhyperfractionationwayarerecommended.

Key words:

margin-bottom: 0pt,text-indent: 24pt,line-height: 150%">Carcinoma,smallcell,Radiotherapy,Limiteddisease