TRIM14在恶性肿瘤中的研究进展

摘要/Abstract

摘要：三重基序蛋白14（TRIM14）是三重基序蛋白家族众多成员之一，具有调控先天免疫反应、影响细胞分化等生理作用。新近研究表明，TRIM14在几种常见肿瘤（非小细胞肺癌、乳腺癌、肝细胞癌、骨肉瘤及口腔鳞状细胞癌）中均有表达，且可通过不同机制影响恶性肿瘤的增殖、浸润、转移、耐药以及肿瘤患者的预后。

杨志贤，侯飞，李浩宇，邓智勇. TRIM14在恶性肿瘤中的研究进展[J]. 国际肿瘤学杂志, 2018, 45(12): 731-734.

Yang Zhixian, Hou Fei, Li Haoyu, Deng Zhiyong. Research progress of TRIM14 in malignant tumors[J]. Journal of International Oncology, 2018, 45(12): 731-734.

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Research progress of TRIM14 in malignant tumors

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