支链氨基酸转移酶1与恶性肿瘤

摘要/Abstract

摘要：支链氨基酸转移酶1(BCAT1)作为催化支链氨基酸代谢的关键酶，参与多种生物合成的通路。研究发现BCAT1在白血病、胶质瘤、鼻咽癌、胃癌、乳腺癌等恶性肿瘤中高表达，与肿瘤细胞的增殖、侵袭及转移密切相关，在肿瘤的发生发展中扮演重要角色，可作为恶性肿瘤新的治疗靶点。

吕天鑫,张兵雷,宋永平. 支链氨基酸转移酶1与恶性肿瘤[J]. 国际肿瘤学杂志, 2019, 46(1): 36-39.

Lyu Tianxin, Zhang Binglei, Song Yongping. Branched chain amino acid transferase 1 and malignant tumors[J]. Journal of International Oncology, 2019, 46(1): 36-39.

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Branched chain amino acid transferase 1 and malignant tumors

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