国际肿瘤学杂志››2022,Vol. 49››Issue (4): 216-219.doi:10.3760/cma.j.cn371439-20210520-00038

• 综述 •上一篇下一篇

焦孔素E与肿瘤

马梅杰, 马慧涵, 秘嘉庆, 秦倩, 冯勤梅()

  1. 山西医科大学附属人民医院妇科,太原 030012
  • 收稿日期:2021-05-20修回日期:2021-11-22出版日期:2022-04-08发布日期:2022-05-11
  • 通讯作者:冯勤梅 E-mail:qmf369@hotmail.com

Gasdermin E and neoplasms

Ma Meijie, Ma Huihan, Mi Jiaqing, Qin Qian, Feng Qinmei()

  1. Department of Gynecology, People’s Hospital Affiliated to Shanxi Medical University, Taiyuan 030012, China
  • Received:2021-05-20Revised:2021-11-22Online:2022-04-08Published:2022-05-11
  • Contact:Feng Qinmei E-mail:qmf369@hotmail.com

摘要:

焦孔素E蛋白与肿瘤关系密切。焦孔素E通过基因甲基化、基因突变或其他方式参与肿瘤的发生发展。焦孔素E介导的焦亡参与多种肿瘤的药物治疗过程,为肿瘤的药物治疗提供了全新的理论基础。深入研究焦孔素E将为肿瘤的认识、诊治提供一种全新的视角。

关键词:细胞焦亡,肿瘤,焦孔素E

Abstract:

Gasdermin E is closely related to neoplasms, which is involved in the occurrence and development of neoplasms through gene methylation, gene mutation or other ways. Pyroptosis mediated by gasdermin E is involved in drug therapy of various neoplasms, which provides a new theoretical basis for drug therapy of neoplasms. The study of gasdermin E aims to deepen the understanding of neoplasms and provide a new perspective for the prevention and treatment of neoplasms.

Key words:Pyroptosis,Neoplasms,Gasdermin E