国际肿瘤学杂志››2023,Vol. 50››Issue (9): 544-547.doi:10.3760/cma.j.cn371439-20230506-00104
叶彤彤, 吴泽宇, 席文一, 王芝微, 江晓春, 赵晨辉()
收稿日期:
2023-05-06修回日期:
2023-05-30出版日期:
2023-09-08发布日期:
2023-10-26通讯作者:
赵晨辉 E-mail:zhaochenhui0510@sina.com基金资助:
Ye Tongtong, Wu Zeyu, Xi Wenyi, Wang Zhiwei, Jiang Xiaochun, Zhao Chenhui()
Received:
2023-05-06Revised:
2023-05-30Online:
2023-09-08Published:
2023-10-26Contact:
Zhao Chenhui E-mail:zhaochenhui0510@sina.comSupported by:
摘要:
ABRACL蛋白是肌动蛋白和细胞运动的调节因子,属于HSPC280家族,其保守的疏水槽可与其他蛋白相互作用,从而增强肌动蛋白动力和细胞活性。ABRACL在肿瘤组织中表达上调,与肿瘤细胞的增殖和迁移关系密切。深入了解ABRACL在肿瘤发生发展中的作用,可为ABRACL预防或逆转肿瘤进展提供新的思路和见解。
叶彤彤, 吴泽宇, 席文一, 王芝微, 江晓春, 赵晨辉. ABRACL在恶性肿瘤发生发展中的作用[J]. 国际肿瘤学杂志, 2023, 50(9): 544-547.
Ye Tongtong, Wu Zeyu, Xi Wenyi, Wang Zhiwei, Jiang Xiaochun, Zhao Chenhui. Role of ABRACL in the occurrence and development of malignant tumors[J]. Journal of International Oncology, 2023, 50(9): 544-547.
[1] | Bakir B, Chiarella AM, Pitarresi JR, et al. EMT, MET, plasticity, and tumor metastasis[J].Trends Cell Biol,2020,30(10): 764-776. DOI:10.1016/j.tcb.2020.07.003. pmid:32800658 |
[2] | Fares J, Fares MY, Khachfe HH, et al. Molecular principles of metastasis: a hallmark of cancer revisited[J].Signal Transduct Target Ther,2020,5(1): 28. DOI:10.1038/s41392-020-0134-x. |
[3] | Hyrskyluoto A, Vartiainen MK. Regulation of nuclear actin dynamics in development and disease[J].Curr Opin Cell Biol,2020,64: 18-24. DOI:10.1016/j.ceb.2020.01.012. pmid:32088545 |
[4] | Li J, Chen H. Actin-binding Rho activating C-terminal like (ABRACL) transcriptionally regulated by MYB proto-oncogene like 2 (MYBL2) promotes the proliferation, invasion, migration and epithelial-mesenchymal transition of breast cancer cells[J].Bioengineered,2022,13(4): 9019-9031. DOI:10.1080/21655979.2022.2056821. pmid:35341461 |
[5] | Lin J, Zhou T, Wang J. Solution structure of the human HSPC280 protein[J].Protein Sci,2011,20(1): 216-223. DOI:10.1002/pro.548. pmid:21082705 |
[6] | Pang TL, Chen FC, Weng YL, et al. Costars, a dictyostelium protein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motility[J].J Cell Sci,2010,123(Pt 21): 3745-3755. DOI:10.1242/jcs.064709. |
[7] | Hsiao BY, Chen CH, Chi HY, et al. Human costars family protein ABRACL modulates actin dynamics and cell migration and associates with tumorigenic growth[J].Int J Mol Sci,2021,22(4): 2037. DOI:10.3390/ijms22042037. |
[8] | Hamidi H, Ivaska J. Every step of the way: integrins in cancer progression and metastasis[J].Nat Rev Cancer,2018,18(9): 533-548. DOI:10.1038/s41568-018-0038-z. pmid:30002479 |
[9] | Novikov NM, Zolotaryova SY, Gautreau AM, et al. Mutational drivers of cancer cell migration and invasion[J].Br J Cancer,2021,124(1): 102-114. DOI:10.1038/s41416-020-01149-0. |
[10] | Ghouzlani A, Kandoussi S, Tall M, et al. Immune checkpoint inhibitors in human glioma microenvironment[J].Front Immunol,2021,12: 679425. DOI:10.3389/fimmu.2021.679425. |
[11] | Youssef G, Miller JJ. Lower grade gliomas[J].Curr Neurol Neurosci Rep,2020,20(7): 21. DOI:10.1007/s11910-020-01040-8. |
[12] | Liu B, Guan Y, Wang M, et al. ABRACL as a potential prognostic biomarker and correlates with immune infiltration in low-grade gliomas[J].Interdiscip Neurosurg,2022,30: 101618. DOI:10.1016/j.inat.2022.101618. |
[13] | Brägelmann J, Lorenz C, Borchmann S, et al. MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG -Ⅰ[J].Nat Commun,2021,12(1): 5505. DOI:10.1038/s41467-021-25728-8. pmid:34535668 |
[14] | Ben-Dror J, Shalamov M, Sonnenblick A. The history of early breast cancer treatment[J].Genes (Basel),2022,13(6): 960. DOI:10.3390/genes13060960. |
[15] | Pastushenko I, Blanpain C. EMT transition states during tumor progression and metastasis[J].Trends Cell Biol,2019,29(3): 212-226. DOI:10.1016/j.tcb.2018.12.001. pmid:30594349 |
[16] | Cao W, Chen HD, Yu YW, et al. Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020[J].Chin Med J (Engl),2021,134(7): 783-791. DOI:10.1097/CM9.0000000000001474. |
[17] | 曹莎莎, 段丽娟, 周福有. 基于TCGA分析ABRACL在食管癌组织中的表达及机制[J].河南医学研究,2021,30(34): 6340-6344. DOI:10.3969/j.issn.1004-437X.2021.34.002. |
[18] | Wang D, Liu H, Ren C, et al. High expression of ABRACL is associated with tumorigenesis and affects clinical outcome in gastric cancer[J].Genet Test Mol Biomarkers,2019,23(2): 91-97. DOI:10.1089/gtmb.2018.0195. |
[19] | Fan S, Chen P, Li S. miR-145-5p inhibits the proliferation, migration, and invasion of esophageal carcinoma cells by targeting ABRACL[J].Biomed Res Int,2021,2021: 6692544. DOI:10.1155/2021/6692544. |
[20] | Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2021,71(3): 209-249. DOI:10.3322/caac.21660. |
[21] | Joshi SS, Badgwell BD. Current treatment and recent progress in gastric cancer[J].CA Cancer J Clin,2021,71(3): 264-279. DOI:10.3322/caac.21657. |
[22] | Zhao Y, Li S, Childs EE, et al. Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-α-induced liver injury[J].J Biol Chem,2001,276(29): 27432-27440. DOI:10.1074/jbc.M102465200. pmid:11369777 |
[23] | Ura B, Monasta L, Arrigoni G, et al. A proteomic approach for the identification of biomarkers in endometrial cancer uterine aspirate[J].Oncotarget,2017,8(65): 109536-109545. DOI:10.18632/oncotarget.22725. |
[24] | Deutsch EW, Omenn GS, Sun Z, et al. Advances and utility of the human plasma proteome[J].J Proteome Res,2021,20(12): 5241-5263. DOI:10.1021/acs.jproteome.1c00657. pmid:34672606 |
[25] | Saghaleyni R, Sheikh Muhammad A, Bangalore P, et al. Machine learning-based investigation of the cancer protein secretory pathway[J].PLoS Comput Biol,2021,17(4): e1008898. DOI:10.1371/journal.pcbi.1008898. |
[26] | Zygulska AL, Pierzchalski P. Novel diagnostic biomarkers in colo-rectal cancer[J].Int J Mol Sci,2022,23(2): 852. DOI:10.3390/ijms23020852. |
[27] | Battaglia RA, Delic S, Herrmann H, et al. Vimentin on the move: new developments in cell migration[J].F1000Res,2018,7:F1000 Faculty Rev-1796. DOI:10.12688/f1000research.15967.1. |
[1] | 刘娜, 寇介丽, 杨枫, 刘桃桃, 李丹萍, 韩君蕊, 杨立洲.血清miR-106b-5p、miR-760联合低剂量螺旋CT诊断早期肺癌的临床价值[J]. 国际肿瘤学杂志, 2024, 51(6): 321-325. |
[2] | 杨蜜, 别俊, 张加勇, 邓佳秀, 唐组阁, 卢俊.局部晚期可切除食管癌新辅助治疗疗效及预后分析[J]. 国际肿瘤学杂志, 2024, 51(6): 332-337. |
[3] | 袁健, 黄燕华.Hp-IgG抗体联合血清DKK1、sB7-H3对早期胃癌的诊断价值[J]. 国际肿瘤学杂志, 2024, 51(6): 338-343. |
[4] | 陈红健, 张素青.血清miR-24-3p、H2AFX与肝癌患者临床病理特征及术后复发的关系研究[J]. 国际肿瘤学杂志, 2024, 51(6): 344-349. |
[5] | 郭泽浩, 张俊旺.PFDN及其亚基在肿瘤发生发展中的作用[J]. 国际肿瘤学杂志, 2024, 51(6): 350-353. |
[6] | 张百红, 岳红云.新作用机制的抗肿瘤药物进展[J]. 国际肿瘤学杂志, 2024, 51(6): 354-358. |
[7] | 许凤琳, 吴刚.EBV在鼻咽癌肿瘤免疫微环境和免疫治疗中的研究进展[J]. 国际肿瘤学杂志, 2024, 51(6): 359-363. |
[8] | 王盈, 刘楠, 郭兵.抗体药物偶联物在转移性乳腺癌治疗中的研究进展[J]. 国际肿瘤学杂志, 2024, 51(6): 364-369. |
[9] | 张蕊, 褚衍六.基于FIT与肠道菌群的结直肠癌风险评估模型的研究进展[J]. 国际肿瘤学杂志, 2024, 51(6): 370-375. |
[10] | 高凡, 王萍, 杜超, 褚衍六.肠道菌群与结直肠癌非手术治疗的相关研究进展[J]. 国际肿瘤学杂志, 2024, 51(6): 376-381. |
[11] | 王丽, 刘志华, 杨伟洪, 蒋凤莲, 李全泳, 宋浩杰, 鞠文东.ROS1突变肺腺鳞癌合并脑梗死为主要表现的Trousseau综合征1例[J]. 国际肿瘤学杂志, 2024, 51(6): 382-384. |
[12] | 刘静, 刘芹, 黄梅.基于SMOTE算法的食管癌放化疗患者肺部感染的预后模型构建[J]. 国际肿瘤学杂志, 2024, 51(5): 267-273. |
[13] | 杨琳, 路宁, 温华, 张明鑫, 朱琳.炎症负荷指数与胃癌临床关系研究[J]. 国际肿瘤学杂志, 2024, 51(5): 274-279. |
[14] | 王俊毅, 洪楷彬, 纪荣佳, 陈大朝.癌结节对结直肠癌根治性切除术后肝转移的影响[J]. 国际肿瘤学杂志, 2024, 51(5): 280-285. |
[15] | 张宁宁, 杨哲, 檀丽梅, 李振宁, 王迪, 魏永志.宫颈细胞DNA倍体分析联合B7-H4和PKCδ对宫颈癌的诊断价值[J]. 国际肿瘤学杂志, 2024, 51(5): 286-291. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||