国际肿瘤学杂志››2012,Vol. 39››Issue (8): 678-679.

• 综述 •上一篇下一篇

诊断肿瘤新型标志物血清miRNA

金儿,马胜林

  1. 310006,杭州市第一人民医院呼吸内科(金儿),肿瘤放疗科(马胜林)
  • 出版日期:2012-09-22发布日期:2012-09-24
  • 通讯作者:马胜林,E-mail: mashenglin@medmail.com.cn E-mail:mashenglin@medmail.com.cn
  • 基金资助:

    杭州市重大科技创新项目(20112313A01)

Serum miRNA:a new marker of cancer diagnosis

JIN 儿, MA Sheng-Lin

  1. Department of Respiratory Medicine, First Hospital of Hangzhou, Hangzhou 310006, China
  • Online:2012-09-22Published:2012-09-24
  • Contact:MA Sheng-lin, E-mail: mashenglin@medmail.com.cn E-mail:mashenglin@medmail.com.cn

摘要:微小RNA(miRNA )功能失调与肿瘤的发生、发展密切相关。血清miRNA不仅具有良好的稳定性,而且有显著的肿瘤相关性和组织特异性。血清miRNA的检测具有获取简便、创伤小、技术快速等优点,因此可作为新的诊断肿瘤的分子标志物。

关键词:微RNAs,肿瘤,诊断

Abstract:Dysfunction of microRNA (miRNA ) is associated with occurrence and development of tumor. MiRNA are very stable in blood serum, significantly tumorrelated and tissuespecific. The detection of serum miRNA is convenient, littleinvasive and fast, and then serum miRNA can be used as a new biomarker for tumor diagnosis.

Key words:MicroRNA,Neoplasms ,Diagnosis