老年三阴性乳腺癌的临床病理特征及治疗

摘要/Abstract

摘要：老年三阴性乳腺癌(TNBC)具有独特的临床病理特征，除浸润性导管癌，也多见于腺癌、小叶癌，该类肿瘤体积大，分级多为Ⅲ级。老年TNBC患者辅助化疗疗效显著，但因常并发其他疾病，选择治疗方案时除考虑肿瘤分期外，还需注意患者重要器官功能及耐受能力。老年TNBC患者预后较差，给予合理治疗后，情况可明显改善。

关键词:病理学,临床,老年人,治疗,乳腺肿瘤

Abstract:Triplenegative breast cancer (TNBC) in elderly patients presents distinctive clinicopathologic characteristics of large volume and histological grade Ⅲ, and it is seen most frequently in invasive ductal carcinoma, adenocarcinoma and lobular carcinoma. Elderly women with TNBC significantly benefit from adjuvant chemotherapy. But older women frequently have concurrent disease, so neoplasm staging, function of vital organs and tolerance of patient should be considered when treatment programs are selected．The prognosis of older TNBC patient is worse, but rational therapy can improve outcomes significantly.

Key words:Pathology, clinical,Aged,Therapy,Breast neoplasms

高静. 老年三阴性乳腺癌的临床病理特征及治疗[J]. 国际肿瘤学杂志, 2013, 40(12): 921-923.

GAO Jing. Clinicopathological features and therapies of elderly women with triplenegative breast cancer[J]. Journal of International Oncology, 2013, 40(12): 921-923.

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