国际肿瘤学杂志››2014,Vol. 41››Issue (11): 833-836.doi:10.3760/cma.j.issn.1673-422X.2014.11.011

• 综述 •上一篇下一篇

MMP-9与结直肠癌侵袭转移的相关性及临床研究进展

  1. 蚌埠医学院第一附属医院肿瘤外二科
  • 出版日期:2014-12-03发布日期:2015-01-20
  • 通讯作者:许培权,Email:xupeiquan2003@aliyun.com

Clinical research progress between MMP-9 and the invasion and metastasis of colorectal cancer

  1. Second Department of Surgical Oncology, First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, China
  • Online:2014-12-03Published:2015-01-20
  • Contact:Xu Peiquan, Email: xupeiquan2003@aliyun.com

摘要:基质金属蛋白酶(MMP)-9是MMP家族相对分子质量最大的MMP,主要来源于巨噬细胞和中性粒细胞,MMP9与结直肠癌的发生及侵袭转移相关,也可以为结直肠癌的临床预防及治疗提供新的途径

关键词:基质金属蛋白酶9,结直肠肿瘤,肿瘤侵润,肿瘤转移

Abstract:The molecular weight of matrix metalloproteinase (MMP)9 is the largest in MMP family which comes mainly from macrophage and neutrophil. MMP9 is considered to be involved in the occurrence and metastasis of colorectal cancer. It also provides a new way for colorectal cancer in clinical prevention and treatment.

Key words:Matrix metalloproteinase 9,Colorectal neoplasms,Neoplasm invasiveness,Neoplasm metastasis