血管紧张素-(1-7)与肿瘤

摘要/Abstract

摘要：血管紧张素-(1-7)［Ang-(1-7)］是近年来发现的肾素血管紧张素系统中一种内源性七肽，与血管紧张素转换酶2（ACE2）及Mas受体共同构成ACE2Ang(17)Mas轴，起到拮抗ACEAngⅡAngⅡ 1型受体轴的作用。近期发现除了其在心血管疾病中发挥作用外，在肿瘤的治疗中也有一定的作用，包括抑制血管生成、抗细胞增殖以及抑制肿瘤纤维化等。研究Ang(17)的作用及作用机制能够为肿瘤的治疗及预防提供新的研究方向。

赵乐康, 于金明 . 血管紧张素-(1-7)与肿瘤[J]. 国际肿瘤学杂志, 2015, 42(4): 274-276.

ZHAO Le-Kang, YU Jin-Ming- . Angiotensin-(1-7) and tumors[J]. Journal of International Oncology, 2015, 42(4): 274-276.

参考文献

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Angiotensin-(1-7) and tumors

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