Journal of International Oncology››2023,Vol. 50››Issue (3): 179-182.doi:10.3760/cma.j.cn371439-20230105-00035
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Wang Yaqian1, Du Yiwei1, Wang Xing1, Jia Junmei2()
Received:
2023-01-05Revised:
2023-01-14Online:
2023-03-08Published:
2023-04-12Contact:
Jia Junmei, Email:
Wang Yaqian, Du Yiwei, Wang Xing, Jia Junmei. Prognostic predictors of immunotherapy in patients with small cell lung cancer[J]. Journal of International Oncology, 2023, 50(3): 179-182.
[1] | Wang S, Zimmermann S, Parikh K, et al. Current diagnosis and management of small-cell lung cancer[J]. Mayo Clin Proc, 2019, 94(8): 1599-1622. DOI: 10.1016/j.mayocp.2019.01.034. doi:S0025-6196(19)30126-0pmid:31378235 |
[2] | Yin X, Li Y, Wang H, et al. Small cell lung cancer transformation: from pathogenesis to treatment[J]. Semin Cancer Biol, 2022, 86(Pt 2): 595-606. DOI: 10.1016/j.semcancer.2022.03.006. doi:10.1016/j.semcancer.2022.03.006pmid:35276343 |
[3] | Rudin CM, Brambilla E, Faivre-Finn C, et al. Small-cell lung cancer[J]. Nat Rev Dis Primers, 2021, 7(1): 3. DOI: 10.1038/s41572-020-00235-0. doi:10.1038/s41572-020-00235-0pmid:33446664 |
[4] | Vafaei S, Zekiy AO, Khanamir RA, et al. Combination therapy with immune checkpoint inhibitors (ICIs); a new frontier[J]. Cancer Cell Int, 2022, 22(1): 2. DOI: 10.1186/s12935-021-02407-8. doi:10.1186/s12935-021-02407-8pmid:34980128 |
[5] | Gadgeel SM, Pennell NA, Fidler MJ, et al. Phase Ⅱ study of maintenance pembrolizumab in patients with extensive-stage small cell lung cancer (SCLC)[J]. J Thorac Oncol, 2018, 13(9): 1393-1399. DOI: 10.1016/j.jtho.2018.05.002. doi:10.1016/j.jtho.2018.05.002 |
[6] | Ricciuti B, Kravets S, Dahlberg SE, et al. Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer[J]. J Immunother Cancer, 2019, 7(1): 87. DOI: 10.1186/s40425-019-0572-6. doi:10.1186/s40425-019-0572-6pmid:30922388 |
[7] | Keogh A, Finn S, Radonic T. Emerging biomarkers and the changing landscape of small cell lung cancer[J]. Cancers (Basel), 2022, 14(15): 3772. DOI: 10.3390/cancers14153772. doi:10.3390/cancers14153772 |
[8] | Benitez JC, Recondo G, Rassy E, et al. The LIPI score and inflammatory biomarkers for selection of patients with solid tumors treated with checkpoint inhibitors[J]. Q J Nucl Med Mol Imaging, 2020, 64(2): 162-174. DOI: 10.23736/S1824-4785.20.03250-1. doi:10.23736/S1824-4785.20.03250-1pmid:32107903 |
[9] | Lee YJ, Lee JB, Ha SJ, et al. Clinical perspectives to overcome acquired resistance to anti-programmed death-1 and anti-programmed death ligand-1 therapy in non-small cell lung cancer[J]. Mol Cells, 2021, 44(5): 363-373. DOI: 10.14348/molcells.2021.0044. doi:10.14348/molcells.2021.0044pmid:34001680 |
[10] | Sun C, Zhang L, Zhang W, et al. Expression of PD-1 and PD-L1 on tumor-infiltrating lymphocytes predicts prognosis in patients with small-cell lung cancer[J]. Onco Targets Ther, 2020, 13: 6475-6483. DOI: 10.2147/OTT.S252031. doi:10.2147/OTT.S252031 |
[11] | Acheampong E, Abed A, Morici M, et al. Tumour PD-L1 expression in small-cell lung cancer: a systematic review and meta-analysis[J]. Cells, 2020, 9(11): 2393. DOI: 10.3390/cells9112393. doi:10.3390/cells9112393 |
[12] | Liu SV, Reck M, Mansfield AS, et al. Updated overall survival and PD-L1 subgroup analysis of patients with extensive-stage small-cell lung cancer treated with atezolizumab, carboplatin, and etoposide (IMpower133)[J]. J Clin Oncol, 2021, 39(6): 619-630. DOI: 10.1200/JCO.20.01055. doi:10.1200/JCO.20.01055pmid:33439693 |
[13] | Iams WT, Porter J, Horn L. Immunotherapeutic approaches for small-cell lung cancer[J]. Nat Rev Clin Oncol, 2020, 17(5): 300-312. DOI: 10.1038/s41571-019-0316-z. doi:10.1038/s41571-019-0316-zpmid:32055013 |
[14] | Tian Y, Zhai X, Han A, et al. Potential immune escape mechanisms underlying the distinct clinical outcome of immune checkpoint blockades in small cell lung cancer[J]. J Hematol Oncol, 2019, 12(1): 67. DOI: 10.1186/s13045-019-0753-2. doi:10.1186/s13045-019-0753-2 |
[15] | Otoshi T, Nagano T, Tachihara M, et al. Possible biomarkers for cancer immunotherapy[J]. Cancers (Basel), 2019, 11(7): 935. DOI: 10.3390/cancers11070935. doi:10.3390/cancers11070935 |
[16] | Sha D, Jin Z, Budczies J, et al. Tumor mutational burden as a predictive biomarker in solid tumors[J]. Cancer Discov, 2020, 10(12): 1808-1825. DOI: 10.1158/2159-8290.CD-20-0522. doi:10.1158/2159-8290.CD-20-0522pmid:33139244 |
[17] | Hellmann MD, Callahan MK, Awad MM, et al. Tumor mutational burden and efficacy of nivolumab monotherapy and in combination with ipilimumab in small-cell lung cancer[J]. Cancer Cell, 2018, 33(5): 853-861. e4. DOI: 10.1016/j.ccell.2018.04.001. doi:S1535-6108(18)30172-7pmid:29731394 |
[18] | Kim ES, Velcheti V, Mekhail T, et al. Blood-based tumor mutational burden as a biomarker for atezolizumab in non-small cell lung cancer: the phase 2 B-F1RST trial[J]. Nat Med, 2022, 28(5): 939-945. DOI: 10.1038/s41591-022-01754-x. doi:10.1038/s41591-022-01754-x |
[19] | Jardim DL, Goodman A, de Melo Gagliato D, et al. The challenges of tumor mutational burden as an immunotherapy biomarker[J]. Cancer Cell, 2021, 39(2): 154-173. DOI: 10.1016/j.ccell.2020.10.001. doi:10.1016/j.ccell.2020.10.001pmid:33125859 |
[20] | Rudin CM, Poirier JT, Byers LA, et al. Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data[J]. Nat Rev Cancer, 2019, 19(5): 289-297. DOI: 10.1038/s41568-019-0133-9. doi:10.1038/s41568-019-0133-9pmid:30926931 |
[21] | Prisciandaro M, Antista M, Raimondi A, et al. Biomarker landscape in neuroendocrine tumors with high-grade features: current knowledge and future perspective[J]. Front Oncol, 2022, 12: 780716. DOI: 10.3389/fonc.2022.780716. doi:10.3389/fonc.2022.780716 |
[22] | Gay CM, Stewart CA, Park EM, et al. Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities[J]. Cancer Cell, 2021, 39(3): 346-360. e7. DOI: 10.1016/j.ccell.2020.12.014. doi:10.1016/j.ccell.2020.12.014pmid:33482121 |
[23] | 金莹, 陈亚梅, 胡晓, 等. 循环肿瘤DNA检测小细胞肺癌基因突变的可行性及其预后预测价值分析[J]. 中华医学杂志, 2020, 100(45): 3614-3621. DOI:10.3760/cma.j.cn112137-20200504-01412. doi:10.3760/cma.j.cn112137-20200504-01412 |
[24] | Roper N, Velez MJ, Chiappori A, et al. Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer[J]. Nat Commun, 2021, 12(1): 3880. DOI: 10.1038/s41467-021-24164-y. doi:10.1038/s41467-021-24164-ypmid:34162872 |
[25] | Hu C, Dong J, Liu L, et al. ASCL1 and DLL3 expressions and their clinicopathological implications in surgically resected pure small cell lung cancer: a study of 247 cases from the National Cancer Center of China[J]. Thorac Cancer, 2022, 13(3): 338-345. DOI: 10.1111/1759-7714.14249. doi:10.1111/1759-7714.14249 |
[26] | Leonetti A, Facchinetti F, Minari R, et al. Notch pathway in small-cell lung cancer: from preclinical evidence to therapeutic challenges[J]. Cell Oncol (Dordr), 2019, 42(3): 261-273. DOI: 10.1007/s13402-019-00441-3. doi:10.1007/s13402-019-00441-3 |
[27] | Tanaka K, Isse K, Fujihira T, et al. Prevalence of delta-like protein 3 expression in patients with small cell lung cancer[J]. Lung Cancer, 2018, 115: 116-120. DOI: 10.1016/j.lungcan.2017.11.018. doi:S0169-5002(17)30585-8pmid:29290251 |
[28] | Li W, Ye L, Huang Y, et al. Characteristics of notch signaling pathway and its correlation with immune microenvironment in SCLC[J]. Lung Cancer, 2022, 167: 25-33. DOI: 10.1016/j.lungcan.2022.03.019. doi:10.1016/j.lungcan.2022.03.019pmid:35381444 |
[29] | Dixon ML, Luo L, Ghosh S, et al. Remodeling of the tumor microenvironment via disrupting Blimp1+effector Treg activity augments response to anti-PD-1 blockade[J]. Mol Cancer, 2021, 20(1): 150. DOI: 10.1186/s12943-021-01450-3. doi:10.1186/s12943-021-01450-3 |
[30] | Bonanno L, Pavan A, Dieci MV, et al. The role of immune microenvironment in small-cell lung cancer: distribution of PD-L1 expression and prognostic role of FOXP3-positive tumour infiltra-ting lymphocytes[J]. Eur J Cancer, 2018, 101: 191-200. DOI: 10.1016/j.ejca.2018.06.023. doi:S0959-8049(18)30937-7pmid:30077124 |
[31] | Jiang M, Wu C, Zhang L, et al. FOXP3-based immune risk model for recurrence prediction in small-cell lung cancer at stages Ⅰ-Ⅲ[J]. J Immunother Cancer, 2021, 9(5): e002339. DOI: 10.1136/jitc-2021-002339. doi:10.1136/jitc-2021-002339 |
[32] | Kanemura H, Hayashi H, Tomida S, et al. The tumor immune microenvironment and frameshift neoantigen load determine response to PD-L1 blockade in extensive-stage SCLC[J]. JTO Clin Res Rep, 2022, 3(8): 100373. DOI: 10.1016/j.jtocrr.2022.100373. doi:10.1016/j.jtocrr.2022.100373 |
[33] | Hardy-Werbin M, Rocha P, Arpi O, et al. Serum cytokine levels as predictive biomarkers of benefit from ipilimumab in small cell lung cancer[J]. Oncoimmunology, 2019, 8(6): e1593810. DOI: 10.1080/2162402X.2019.1593810. doi:10.1080/2162402X.2019.1593810 |
[34] | Li L, Pi C, Yan X, et al. Prognostic value of the pretreatment lung immune prognostic index in advanced small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors plus chemotherapy[J]. Front Oncol, 2021, 11: 697865. DOI: 10.3389/fonc.2021.697865. doi:10.3389/fonc.2021.697865 |
[35] | Qi WX, Xiang Y, Zhao S, et al. Assessment of systematic inflammatory and nutritional indexes in extensive-stage small-cell lung cancer treated with first-line chemotherapy and atezolizumab[J]. Cancer Immunol Immunother, 2021, 70(11): 3199-3206. DOI: 10.1007/s00262-021-02926-3. doi:10.1007/s00262-021-02926-3 |
[36] | Zhou K, Cao J, Lin H, et al. Prognostic role of the platelet to lymphocyte ratio (PLR) in the clinical outcomes of patients with advanced lung cancer receiving immunotherapy: a systematic review and meta-analysis[J]. Front Oncol, 2022, 12: 962173. DOI: 10.3389/fonc.2022.962173. doi:10.3389/fonc.2022.962173 |
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