Journal of International Oncology››2014,Vol. 41››Issue (1): 27-30.doi:10.3760/cma.j.issn.1673-422X.2014.01.009

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Bevacizumab for glioma and radiation encephalic necrosis

Pan Xuefeng, Xing Hongyu, Zheng Guobao

  1. Department of Oncology, 150th Central Hospital of the People′s Liberation Army, Luoyang 471031, China
  • Online:2014-01-08Published:2014-01-22
  • Contact:Pan Xuefeng E-mail:panxf-2004@163.com

Abstract:The U.S. Food and Drug Administration approves bevacizumab for salvage therapy of glioblastoma in 2009, which is the first monoclonal antibody of antiangiogenesis in the global. Afterwards, bevacizumab for malignant glioma becomes the focus of research, but the latest studies do not support its use for the firstline treatment of malignant glioma. Furthermore, bevacizumab shows a encouraging effect for radiation encephalic necrosis and its final outcome remains to be further confirmed.

Key words:Glioma,Radiation injuries,Brain,Bevacizumab