Journal of International Oncology››2014,Vol. 41››Issue (3): 203-205.doi:10.3760/cma.j.issn.1673-422X.2014.03.013

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Significance of histologic molecular markers for prognosis of the ⅢA (N2) phase non-small cell lung cancer

TANG Shi-Min, LI Wen-Hui, CHANG Li

  1. Department of Radiation Oncology, Third Affiliated Hospital of Kunming Medical University, Kunming 650118, China
  • Online:2014-03-08Published:2014-03-17
  • Contact:Li Wenhui, E-mail: wenhuili64@aliyun.com E-mail:wenhuili64@aliyun.com

Abstract:Prognosis factors of ⅢA (N2) phase nonsmall cell lung cancer are various. The histological molecular markers are mainly about multiresistant gene, growth factors, mucin 4, insulinlike growth factor-2, Ki-67, PTEN and so on. Different expressions of these genes may divide the N2 non-small-cell lung cancer into different molecular subtypes, which is more effective to guide clinical therapy.

Key words:Histology,Biological markers,Neoplasm staging,Carcinoma, nonsmall cell lung,Prognosis