Journal of International Oncology››2017,Vol. 44››Issue (7): 537-540.doi:10.3760/cma.j.issn.1673-422X.2017.07.015

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Expression and significance of tetraspanin in gastric cancer

Nie Xiaofei, Qiu Zhenkang, Liu Ning, Qi Weiwei, Ding Aiping, Qiu Wensheng

  1. Department of Oncology, Affiliated Hospital of Qingdao University, Qingdao 266071, China
  • Received:2016-12-05Online:2017-07-08Published:2017-06-20
  • Contact:Qiu Wensheng E-mail:wsqiuqd@163.com
  • Supported by:

    National Natural Science Foundation of China (81472338)

Abstract:Tetraspanins are a class of cell surface glycoproteins that are expressed very broadly, which can form a complex tetraspanins net by combining with many kinds of cell surface molecules such as integrins, signal proteins, growth factors and so on. In recent years, more and more studies suggest that tetraspanins are closely related to the invasion and metastasis of malignancies and show a certain clinical value, which can be used as new diagnosis and prognosis indicators of malignancy.

Key words:Stomach neoplasms,Prognosis,Tetraspanins