Journal of International Oncology››2017,Vol. 44››Issue (8): 615-618.doi:10.3760/cma.j.issn.1673-422X.2017.08.015

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MicroRNAs and ovarian cancer

Hua Dingchao, Wang Xinyu

  1. Department of Gynecologic Oncology, Affiliated Women′ s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China; Department of Obstetrics and Gynecology, Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 322000, China
  • Online:2017-08-08Published:2017-07-21
  • Contact:Wang Xinyu, Email: wangxy@zju.edu.cn E-mail:wangxy@zju.edu.cn

Abstract:The abnormal expressions of microRNAs (miRNAs) are closely related to the genesis and development of ovarian cancer. MiRNAs are involved in carcinogenesis and progression, invasion and metastasis as well as drug resistance. As a kind of significant biomarker, miRNAs are expected to be novel targets for the early diagnosis and prognostic evaluation of ovarian cancer, which provide new ways for the therapy of ovarian cancer.

Key words:MicroRNAs,Ovarian neoplasms,Drug resistance, neoplasms,Epithelialmesenchymal transition,Neoplasm invasiveness