Abstract:Objective To study the characteristics of diffusion tensor imaging (DTI) in brain tumor and it's diagnosis and differential diagnosis value. Methods Thirty-nine patients with brain tumors proven by pathologically (10 meningioma, 17 glioma, 12 metastatic tumors), using Philips Achieva 1.5 T MRI, conventional MRI and DTI were underwent on them, fractional anisotropy (FA) maps, apparent diffusion coefficient (ADC) maps and three dimensional white matter fiber bundle map were reconstructed in the workstation, selected the core substance of the tumor area and the contralateral mirror area as the region of interest, measured FA and ADC values of them, and t test was performed,P＜0.05was regarded asthe difference have statistically significant. Results The FA values of meningioma, metastases tumors and gliomas were 0.36±0.08, 0.28±0.03, 0.18±0.06, respectively, meningioma is the highest, followed by metastases tumors, and gliomas is the lowest. FA values between meningiomas and metastases tumors, meningiomas and gliomas, metastases tumors and gliomas had significant differences (P＜0.05). The ADC values of meningioma, metastases tumors and gliomas were 1.72±0.10, 1.52±0.22, 1.34±0.14, respectively, meningioma is the highest, followed by metastases tumors, and gliomas is the lowest. ADC values between meningiomas and metastases tumors, meningiomas and gliomas, metastases tumors and gliomas had significant differences (P＜0.05). Conclusion DTI has high clinical value in identification of meningiomas, metastatic tumors and glioma.

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