Journal of International Oncology››2011,Vol. 38››Issue (8): 596-598.

Previous ArticlesNext Articles

Research advance of Dendritic cell vaccines to combat glioma

XU Hao, WANG Zhan-Xiang

    • Received:2011-03-15Revised:2011-07-12Online:2011-08-08Published:2011-08-29

    Abstract:Dendritic cell (DC)-based vaccine therapies represent a novel experimental approach to treat malignant gliomas.Target selection heightens the specificity of vaccine,while engineering of highly immunogenic long-lived DC vaccines by antiapoptotic protein gene transfer enhances the cancer vaccine potency.With the accumulation of clinical experience,it can improve clinical curative effect in the treatment of paitients.

    Key words:Dendritic cell,Glioma,Cancer vaccines,Immunotherapy