Abstract:Epidermal growth factor receptor (EGFR) express highly or mutant in esophageal cancer, which causing tumor resistance to radiotherapy and leading topoor radiotherapeutic effects. Treatment with anti-EGFR can get radiosensitization. There are three main types of molecular targeted research for EGFR: synthetic monoclonal antibody, small molecule tyrosine kinase inhibitors, and other strategies modulating EGFR biosynthesis based on RNA interference.

Key words:

line-height: 150%">color: black,line-height: 150%">Esophageal neoplasms,line-height: 150%,mso-bidi-font-size: 7.5pt">Receptor, epidermal growth factor,color: black,line-height: 150%">RNA interference