Abstract:Although locoregional recurrence (LRR) after mastectomy is regarded as a signal of disease progression, but it is different from distant metastasis. Some patients could have better prognosis and benefit from salvage treatments, especially for patients with isolated LRR. Time to recurrence, site of recurrence and number of recurrent nodules have great influence on the prognosis of patients with LRR. For suited patients with LRR, surgical resection and endocrine therapy are valuable in suitable cases, but the role of chemotherapy still need further study.

Key words:Breast neoplasms,Mastectomy,Prognosis,Therapy