Journal of International Oncology››2014,Vol. 41››Issue (11): 811-812.doi:10.3760/cma.j.issn.1673-422X.2014.11.004

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Cyclin-dependent kinase 10 and tumorigenesis

  1. Department of Pharmacy, Luohe Medical College, Luohe 462002, China
  • Online:2014-12-03Published:2015-01-20
  • Contact:You Yanjie, Email: youyanjie@163.com

Abstract:Cyclindependent kinase 10 (CDK10) function as a tumor suppressor gene through regulating cell cycle interacting with transcription factor Ets2. Studies demonstrate that the downregulation of CDK10 expression occurs in multiple cancer types, indicating a potential application of CDK10 as a molecular diagnostic marker as well as therapeutic target.

Key words:Genes, tumor suppressor,Neoplasms,Tumor markers, biological,Diagnosis