Abstract:EML4ALK fusion gene is one of the novel targets in the therapy of lung cancer, which can be detected in several kinds of tumors. A specific ALK inhibitor has been shown to exert antitumor effects in nonsmall cell lung cancer with the EML4ALK fusion gene. Correlative study between EML4ALK gene fusion and EGFRKras mutations might cast new insight on the tumor target therapy.

Key words:Neoplasms,EML4ALK fusion gene