Functional mechanism of SIRT1 gene in tumor

Abstract

Ma Wei, Lu Ying, Mao Jun, Zhao Wenyue, Li Lianhong. Functional mechanism of SIRT1 gene in tumor[J]. Journal of International Oncology, 2015, 42(1): 40-42.

［1］ Liu T, Liu PY, Marshall GM. The critical role of the class Ⅲ histone deacetylase SIRT1 in cancer［J］. Cancer Res, 2009, 69(5): 1702-1705. ［2］ Zhu X, Liu Q, Wang M, et al. Activation of Sirt1 by resveratrol inhibits TNFα induced inflammation in fibroblasts［J］. PLoS One, 2011, 6(11): e27081. ［3］ Sestito R, Madonna S, Scarponi C, et al. STAT3dependetnt effects of IL22 in human keratinocytes are counterregulated by sirtuin 1 through a diect inhibiton of STAT3 acetylation［J］. FASEB J, 2010, 25(3): 916-927. ［4］ Semenza G. HIF1: upstream and downstream of cancer metabolism［J］. Curr Opin Genet Dev, 2010, 20(1): 51-56. ［5］ Leiser SF, Kaeberlein M. A role for SIRT1 in the hypoxic response［J］. Mol Cell, 2010, 38(6): 779-780. ［6］ Yuan J, MinterDykhouse K, Lou Z. A cMycSIRT1 feedback loop regulates cell growth and transformation［J］. J Cell Biol, 2009, 185(2): 203-211. ［7］ Wang RH, Zheng Y, Kim HS, et al. Interplay among BRCA1, SIRT1, and Survivin during BRCA1associated tumorigenesis［J］. Mol Cell, 2008, 32(1): 11-20. ［8］ Suzuki M, Bartlett JD. Sirtuin1 and autophagy protect cells from fluorideinduced cell stress［J］. Biochim Biophys Acta, 2014, 1842(2): 245-255. ［9］ Firestein R, Blander G, Michan S, et al. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth［J］. PLoS One, 2008, 3(4): e2020. ［10］ Yi J, Luo J. SIRT1 and p53, effect on cancer, senescence and beyond［J］. Biochim Biophys Acta, 2010, 1804(8): 1684-1689. ［11］ Yamakuchi M. MicroRNA regulation of SIRT1［J］. Front Physiol, 2012, 3: 68. ［12］ Dehennaut V, Loison I, Pinte S, et al. Molecular dissection of the interaction between HIC1 and SIRT1［J］. Biochem Biophys Res Commun, 2012, 421(2): 384-388. ［13］ Chen HC, Jeng YM, Yuan RH, et al. SIRT1 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma and its expression predicts poor prognosis［J］. Ann Surg Oncol, 2012, 19(6): 2011-2019. ［14］ Qu Y, Zhang J, Wu S, et al. SIRT1 promotes proliferation and inhibits apoptosis of human malignant glioma cell lines［J］. Neurosci Lett, 2012, 525(2): 168-172. ［15］ Eades G, Yao Y, Yang M, et al. miR200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)like transformation in mammary epithelial cells［J］. J Biol Chem, 2011, 286(29): 25992-26002. ［16］ Byles V, Zhu L, Lovaas JD, et al. SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis［J］. Oncogene, 2012, 31(43): 4619-4629. ［17］ Holloway KR, Calhoun TN, Saxena M, et al. SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling［J］. Proc Natl Acad Sci USA, 2010, 107(20): 9216-9221. ［18］ Oh WK, Cho KB, Hien TT, et al. Amurensin G, a potent natural SIRT1 inhibitor, rescues doxorubicin responsiveness via downregulation of multidrug resistance 1［J］. Mol Pharmacol, 2010, 78(5): 855-864. ［19］ Chang CJ, Hsu CC, Yung MC, et al. Enhanced radiosensitivity and radiationinduced apoptosis in glioma CD133positive cells by knockdown of SirT1 expression［J］. Biochem Biophys Res Commun, 2009, 380(2): 236242. ［20］ Li L, Wang L, Li L, et al. Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib［J］. Cancer Cell, 2012, 21(2): 266-281. ［21］ Nalls D, Tang SN, Rodova M, et al. Targeting epigenetic regulation of miR34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells［J］. PLoS One, 2011, 6(8): e24099.

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Functional mechanism of SIRT1 gene in tumor

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