食管癌新辅助治疗参与保存器官的研究进展

摘要/Abstract

摘要：

食管鳞状细胞癌是我国常见的恶性肿瘤类型之一。局部晚期食管鳞状细胞癌是一种复杂的异质性疾病,治疗方法不断发展。目前,放化疗及手术等多学科综合治疗为其主要手段。然而,由于食管所处的特殊解剖部位,手术切除对患者的生理功能影响较大。在不影响患者整体疗效的基础上,采用保存食管的非手术治疗方法,对于改善患者生命质量等具有重要的意义。新辅助治疗作为一种非侵入性肿瘤治疗手段,在保存食管的综合治疗中扮演重要角色。近年来,陆续有新辅助治疗参与保存食管的食管癌综合治疗策略的研究,对这些研究进展的认识将为食管癌的综合治疗提供参考价值。

关键词:食管肿瘤,新辅助治疗,保存器官,综合治疗

Abstract:

Esophageal squamous cell carcinoma is one of the most common cancer in China, and locally advanced stage remains a heterogeneous and complex disease. Its treatments are constantly evolving. To date, radiochemotherapy and surgery are involved in the comprehensive treatment of this disease. However, because of the specifical anatomical location of esophagus, its physiological function will be impaired after surgical resection. If similar survival is obtained in esophageal cancer, an organ preserving strategy without surgery is of great significance for improving the quality of life. As a non-invasive tumor treatment method, neoadjuvant therapy plays an important role in the comprehensive treatment of preserving the esophagus. Recently, there are studies investigating the role of organ preserving strategy in the comprehensive treatment of esophageal cancer with neoadjuvant therapy, and the recognition of these advances will provide reference value for the comprehensive treatment of esophageal cancer.

Key words:Esophageal neoplasms,Neoadjuvant therapy,Organ preservation,Comprehensive treatment

杜晨, 苏思雨, 王利革, 于桂萍. 食管癌新辅助治疗参与保存器官的研究进展[J]. 国际肿瘤学杂志, 2021, 48(11): 673-677.

Du Chen, Su Siyu, Wang Lige, Yu Guiping. Advances in neoadjuvant therapy of esophageal cancer involved in organ preservation[J]. Journal of International Oncology, 2021, 48(11): 673-677.

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