孤立性磨玻璃结节样肺腺癌的影像组学研究进展

摘要/Abstract

摘要：

表现为磨玻璃结节（GGN）的早期肺腺癌检出率不断升高,在精准靶向治疗发展的时代背景下,更需要基于多模态的影像组学（RM）及影像基因组学等非侵入性检查,以辅助诊断、治疗方案制定及随访,减轻临床负担。RM可分析GGN样肺腺癌不同成分、分析瘤周区域、辅助减少过度诊疗、帮助靶向治疗选择及辅助随访,在孤立性GGN样肺腺癌的诊疗中将发挥越来越重要的作用。

关键词:癌,非小细胞肺,磨玻璃结节,影像组学,肿瘤异质性,肿瘤微环境

Abstract:

The detection of early lung adenocarcinoma manifesting as ground glass nodule （GGN） is increasing. The promoting precision targeted therapy arises the need of radiomics （RM） and radiogenomics, a series of noninvasively radiological technology based on multiple modality, to assist the process including determination in diagnosis, treatment and follow-up strategy and release burden in clinical practice. RM, playing an important role in lung adenocarcinoma manifesting as GGN, can provide information towards the different components of the nodules, the analysis of peritumoral areas, the reduction of over diagnosis and treatment, the selection of targeted therapy and follow-up.

Key words:Carcinoma, non-small-cell lung,Ground glass nodules,Radiomics,Tumor heterogeneity,Tumor microenvironment

吴嘉钰, 刘加成. 孤立性磨玻璃结节样肺腺癌的影像组学研究进展[J]. 国际肿瘤学杂志, 2022, 49(8): 449-452.

Wu Jiayu, Liu Jiacheng. Research progress of radiomics toward lung adenocarcinoma manifesting as solitary ground glass nodule[J]. Journal of International Oncology, 2022, 49(8): 449-452.

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